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SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE

SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Structure
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE
  • CAS No.7782-85-6
  • Chemical Name:SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE
  • CBNumber:CB4362537
  • Molecular Formula:H6NaO5P
  • Formula Weight:140.01
  • MOL File:7782-85-6.mol
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Property
  • Melting point 48 °C
  • bulk density 800kg/m3
  • Density 1.68 g/mL at 25 °C(lit.)
  • vapor density 4.9 (vs air)
  • storage temp. Store at +5°C to +30°C.
  • solubility 154g/l
  • form Solid
  • color White
  • Specific Gravity 1.7
  • PH Range 8.7 - 9.3
  • PH 8.7-9.3 (25℃, 5% in solution)
  • Water Solubility Soluble in water and insoluble in ethanol.
  • Merck 14,8659
  • LogP -2.148 (est)
  • CAS DataBase Reference 7782-85-6(CAS DataBase Reference)
  • Indirect Additives used in Food Contact Substances SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE
  • FDA UNII 70WT22SF4B
  • EPA Substance Registry System Disodium phosphate heptahydrate (7782-85-6)
  • UNSPSC Code 12352302
  • NACRES NA.25
Safety
  • Hazard Codes  :Xi
  • Risk Statements  :36/37/38
  • Safety Statements  :26-36-24/25
  • RIDADR  :UN 3077 9 / PGIII
  • WGK Germany  :2
  • RTECS  :WC4600000
  • TSCA  :Yes
  • HS Code  :28352990
  • Toxicity :LD50 orally in Rabbit: 12930 mg/kg
  • NFPA 704:
    0
    1 1
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Price More Price(17)
  • Brand: Sigma-Aldrich(India)
  • Product number: S9390
  • Product name : Sodium phosphate dibasic heptahydrate
  • Purity: ACS reagent, 98.0-102.0%
  • Packaging: 100G
  • Price: ₹2010
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: S9390
  • Product name : Sodium phosphate dibasic heptahydrate
  • Purity: ACS reagent, 98.0-102.0%
  • Packaging: 500G
  • Price: ₹5110
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: S9390
  • Product name : Sodium phosphate dibasic heptahydrate
  • Purity: ACS reagent, 98.0-102.0%
  • Packaging: 1KG
  • Price: ₹9430
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: S9390
  • Product name : Sodium phosphate dibasic heptahydrate
  • Purity: ACS reagent, 98.0-102.0%
  • Packaging: 2.5KG
  • Price: ₹15436.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: S2429
  • Product name : Sodium phosphate dibasic heptahydrate
  • Purity: meets USP testing specifications
  • Packaging: 250G
  • Price: ₹10023.95
  • Updated: 2022/06/14
  • Buy: Buy

SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Chemical Properties,Usage,Production

  • Chemical Properties The USP 32 states that dibasic sodium phosphate is dried or contains, 1, 2, 7, or 12 molecules of water of hydration. Anhydrous dibasic sodium phosphate occurs as a white powder. The dihydrate occurs as white or almost white, odorless crystals.
    The heptahydrate occurs as colorless crystals or as a white granular or caked salt that effloresces in warm, dry air. The dodecahydrate occurs as strongly efflorescent, colorless or transparent crystals.
  • Uses Sodium Phosphate Dibasic Heptahydrate is used as precursor in the preparation of cobalt-based molecular catalyst for water oxidation.
  • Uses Buffering agent.
  • Uses Sodium phosphate dibasic heptahydrate has been used to prepare sodium phosphate buffer and phosphate-buffered saline (PBS) buffer.[44}
  • Production Methods Either bone phosphate (bone ash), obtained by heating bones to whiteness, or the mineral phosphorite is used as a source of tribasic calcium phosphate, which is the starting material in the industrial production of dibasic sodium phosphate.
    Tribasic calcium phosphate is finely ground and digested with sulfuric acid. This mixture is then leached with hot water and neutralized with sodium carbonate, and dibasic sodium phosphate is crystallized from the filtrate.
  • Pharmaceutical Applications Dibasic sodium phosphate is used in a wide variety of pharmaceutical formulations as a buffering agent and as a sequestering agent. Therapeutically, dibasic sodium phosphate is used as a mild laxative and in the treatment of hypophosphatemia.
    Dibasic sodium phosphate is also used in food products; for example as an emulsifier in processed cheese.
  • Safety Dibasic sodium phosphate is widely used as an excipient in parenteral, oral, and topical pharmaceutical formulations. Phosphate occurs extensively in the body and is involved in many physiological processes since it is the principal anion of intracellular fluid. Most foods contain adequate amounts of phosphate, making hypophosphatemia (phosphate deficiency) virtually unknown except for certain disease states or in patients receiving total parenteral nutrition. Treatment is usually by the oral administration of up to 100 mmol of phosphate daily.
    Approximately two-thirds of ingested phosphate is absorbed from the gastrointestinal tract, virtually all of it being excreted in the urine, and the remainder is excreted in the feces.
    Excessive administration of phosphate, particularly intravenously, rectally, or in patients with renal failure, can cause hyperphosphatemia that may lead to hypocalcemia or other severe electrolyte imbalances. Adverse effects occur less frequently following oral consumption, although phosphates act as mild saline laxatives when administered orally or rectally. Consequently, gastrointestinal disturbances including diarrhea, nausea, and vomiting may occur following the use of dibasic sodium phosphate as an excipient in oral formulations. However, the level of dibasic sodium phosphate used as an excipient in a pharmaceutical formulation is not usually associated with adverse effects.
    LD50 (rat, oral): 17 g/kg
  • storage The anhydrous form of dibasic sodium phosphate is hygroscopic. When heated to 40℃, the dodecahydrate fuses; at 100℃ it loses its water of crystallization; and at a dull-red heat (about 240℃) it is converted into the pyrophosphate, Na4P2O7. Aqueous solutions of dibasic sodium phosphate are stable and may be sterilized by autoclaving.
    The bulk material should be stored in an airtight container, in a cool, dry place.
  • Incompatibilities Dibasic sodium phosphate is incompatible with alkaloids, antipyrine, chloral hydrate, lead acetate, pyrogallol, resorcinol and calcium gluconate, and ciprofloxacin. Interaction between calcium and phosphate, leading to the formation of insoluble calcium-phosphate precipitates, is possible in parenteral admixtures.
  • Regulatory Status GRAS listed. Accepted in Europe for use as a food additive. Included in the FDA Inactive Ingredients Database (injections; infusions; nasal, ophthalmic, oral, otic, topical, and vaginal preparations). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Suppliers
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SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE Spectrum
7782-85-6, SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATERelated Search:
  • 高端化学
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  • 无机化工
  • 无机化合物和盐
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  • 生化试剂
  • 生化试剂-其他化学试剂
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  • 有机化工原料
  • 其他生化试剂
  • 微生物
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  • Synthetic Reagents
  • Puriss p.a.
  • Inorganic Salts
  • General Use
  • Analytical Chromatography Product Catalog
  • Analytical Reagents
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  • 七水合磷酸氢二钠 分析纯
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  • 七水磷酸氢二钠
  • 磷酸氢二钠七水合物
  • 七水磷酸氢二钠, ACS, 98.0-102.0%
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  • 磷酸氢二钠七水合物, 用于分析
  • 磷酸氢二钠七水合物(七水磷酸氢二钠、七水磷酸氢二钠)
  • 磷酸钠 二元 七水合物
  • 7782-85-6
  • DI-SODIUM HYDROGEN ORTHOPHOSPHATE HEPTAHYDRATE
  • meets USP testing specifications
  • SODIUM PHOSPHATE DIBASIC HEPTAHYDRATE AR
  • Sodium Phosphate Dibasic Heptahydrate ACS, 98-102%
  • Sodium phosphate bibasic heptahydrate
  • Dibasic Sodium Phosphate heptahydrate USP 5KG
  • Dibasic Sodium Phosphate heptahydrate USP 500GM
  • Disodiumhosphate heptahydrate
  • SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE ISO 9001：2015 REACH
  • Sodium Phosphate Dibasic, Heptahydrate, USP, EP
  • Sodium phosphate dibasic heptahydrate, 98%, for analysis,Sulfate Compounds:≤0.005% (SO42-)
  • Sodium phosphate dibasic heptahydrate, 98%, for analysis
  • Di Sodium Phosphate HEPTAHYDRATE USP
  • OmniPur Sodium Phosphate, Dibasic, Heptahydrate - CAS 7782-85-6 - Calbiochem
  • SODIUM PHOSPHATE 2BAS 7HYD XTL
  • Phosphoricacid, disodium salt, heptahydrate(8CI,9CI)
  • SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE, REAGENT (ACS)SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE, REAGENT (ACS)SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE, REAGENT (ACS)SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE, REAGENT (ACS)

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