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FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine Property

Melting point 130.5-135.5 °C(lit.)
alpha 25 º (c=1,EtOAc 24 ºC)
Boiling point 510.36°C (rough estimate)
Density 1.2369 (rough estimate)
refractive index 24 ° (C=1, AcOEt)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder to crystal
pka 3.44±0.10(Predicted)
color White to Almost white
optical activity [α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN 3632013
InChI InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey REITVGIIZHFVGU-IBGZPJMESA-N
SMILES C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference 71989-33-8(CAS DataBase Reference)
FDA UNII ZK6MDK63M3
UNSPSC Code 12352209
NACRES NA.26

Safety

NFPA 704:

Hazard and Precautionary Statements (GHS)

FMOC-O-tert-Butyl-L-serine Price More Price(14)

FMOC-O-tert-Butyl-L-serine Chemical Properties,Usage,Production

Chemical Properties white to light yellow crystal powde
Uses Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:
- Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
- Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
- Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.
General Description The product number for this product was previously 04-12-1033.

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reaction suitability reaction type: Fmoc solid-phase peptide synthesis

FMOC-O-tert-Butyl-L-serine Preparation Products And Raw materials

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FMOC-O-tert-Butyl-L-serine Spectrum

71989-33-8, FMOC-O-tert-Butyl-L-serineRelated Search:

Amino Acids
Fluorenes, Flurenones
Fmoc-Amino Acids and Derivatives
Serine [Ser, S]
Fmoc-Amino acid series
Fmoc-Amino Acids
Biochemistry
Amino Acids (N-Protected)
有机原料
医用原料
杂质对照品
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化工原料及中间体
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保护氨基酸(AA)-丝氨酸（Ser）
保护氨基酸-丝氨酸(Ser)
多肽原料药
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多肽-氨基酸
保护氨基酸系列-Fmoc-氨基酸
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Peptide Synthesis
C22H24NO5
C22H25NO5
71686-33-8
29223-22-9
O叔丁基N[(9H芴9基甲氧基)羰基]L丝氨酸/HPLC
化合物 FMOC-SER(TBU)-OH
N-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-O-(TERT-BUTYL)-L-SERINE
FMOC-L-丝氨酸(TBU)
FMOC-SER(TBU)-OH(丝氨酸)
FMOC-O-叔丁基-L-丝氨酸 (FMOC-SER(TBU)-OH)
FMOC-丝氨酸(TBUCHEMICALBOOK)
L-丝氨酸-N-FMOC,O-叔丁基醚(1-13C,99%)
L-丝氨酸-N-FMOC,O-叔丁基醚(13C3
O-TERT-BUTYL-N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-SERINE O-叔丁基-N-[(9H-芴-9-基甲氧基)羰基]-L-丝氨酸