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Dihydrokawain

Dihydrokawain Structure
Dihydrokawain
  • CAS No.587-63-3
  • Chemical Name:Dihydrokawain
  • CBNumber:CB4314738
  • Molecular Formula:C14H16O3
  • Formula Weight:232.27
  • MOL File:587-63-3.mol
Dihydrokawain Property
  • Melting point 58-60°
  • alpha D24 +31° (methanol)
  • Boiling point 314.44°C (rough estimate)
  • Density 1.1649 (rough estimate)
  • refractive index 1.5557 (estimate)
  • storage temp. 2-8°C
  • solubility DMF:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
    DMSO:25.0(Max Conc. mg/mL);107.62(Max Conc. mM)
    Ethanol:5.0(Max Conc. mg/mL);21.52(Max Conc. mM)
  • form Solid
  • color White to off-white
  • optical activity [α]/D 29±2°, c = 0.5 in methanol
  • BRN 15362
  • InChIKey VOOYTQRREPYRIW-LBPRGKRZSA-N
  • LogP 1.950 (est)
  • FDA UNII NW8ZGW9XRZ
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P264-P270-P301+P312+P330-P501
Dihydrokawain Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: 41866
  • Product name : (S)-(+)-7,8-Dihydrokavain
  • Purity: analytical standard
  • Packaging: 5MG
  • Price: ₹42618.03
  • Updated: 2022/06/14
  • Buy: Buy

Dihydrokawain Chemical Properties,Usage,Production

  • Chemical Properties White-pale yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of kava-kava (Piper methysticum G. Forst).
  • Uses (+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
  • Definition ChEBI: Dihydrokavain is a member of 2-pyranones and an aromatic ether.
  • Application Dihydrokavain is one of the six major kavalactones found in the kava plant; appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.Used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
  • Preparation Starting from 2,3-O-isopropylidene-D-glyceraldehyde (2) as chiral material, the naturally occurring (S)-(+)-dihydrokavain (1a) was synthesized by a procedure that involves a sonochemical Blaise reaction as the key step. The absolute configuration of (S)-(+)-dihydrokavain (1a) is demonstrated for the first time by total synthesis from a chiral source. Its opposite enantiomer, (R)-(–)-dihydrokavain (1b), was also synthesized after inversion of the chiral center in a Mitsunobu reaction.
    A Total Synthesis of (+)- and (–)-Dihydrokavain with a Sonochemical Blaise Reaction as the Key Step
Dihydrokawain Preparation Products And Raw materials
Raw materials
Preparation Products
Dihydrokawain Suppliers
Global(138)Suppliers
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
Dihydrokawain Spectrum
587-63-3, DihydrokawainRelated Search:
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  • 植物提取物
  • 二氢醉椒素,10 MM DMSO 溶液
  • (+)-(S)-DIHYDROKAVAIN
  • 二氢醉椒素, 来源于卡瓦胡椒
  • 二氢醉椒素
  • 4-甲氧基-6-苯乙基-5,6-二氢吡喃-2-酮
  • 587-63-3
  • Dihydrokavain, 10 mM in DMSO
  • Dihydrokavain-RM
  • 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethyl)-, (6S)-
  • Dihydrokavain, 98%, from Piper methysticum Forst
  • Dihydrokavain (7,8-Dihydrokawain
  • 7,8-Dihydrokavain
  • (6R)-4-Methoxy-6-phenethyl-5,6-dihydro-2H-pyran-2-one
  • dihydro-kawai
  • 6-dihydro-4-methoxy-6-(2-phenylethyl)-(s)-2h-pyran-2-on
  • DIHYDROKAVAIN(P)
  • 5,6-dihydro-4-methoxy-6-phenethyl-2h-pyran-2-on
  • 7,8-DIHYDROKAWAIN
  • MARINDININ
  • DIHYDROKAVAIN
  • DIHYDROKAWAIN
  • (S)-(+)-7,8-Dihydrokavain
  • (6S)-5,6-Dihydro-4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one
  • 4-methoxy-2-(2-phenylethyl)-2,3-dihydropyran-6-one
  • 4-Methoxy-6-phenethyl-5,6-dihydropyran-2-one
  • (R)-5,6-Dihydro-4-methoxy-6-phenethyl-2H-pyran-2-one

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