AMASTATIN

AMASTATIN Property

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Hazard and Precautionary Statements (GHS)

AMASTATIN Chemical Properties,Usage,Production

Uses Amastatin is A slow, tightly bound, competitive inhibitor of aminopeptidase (AP) with an IC50 of 0.54 μg/mL for AP-A[1][2].
Definition ChEBI: A tetrapeptide comprising (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl, L-valyl, L-valyl and L-aspartic acid units joined in sequence
References [1] Aoyagi T, et al. Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes. J Antibiot (Tokyo). 1978 Jun;31(6):636-8. DOI:10.7164/antibiotics.31.636
[2] Wilkes SH, et al. The slow, tight binding of bestatin and amastatin to aminopeptidases. J Biol Chem. 1985 Oct 25;260(24):13154-62. PMID:2865258

AMASTATIN Preparation Products And Raw materials

Raw materials

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AMASTATIN Spectrum

67655-94-1, AMASTATINRelated Search:

inhibitor
抑制剂
C21H38N4O8
化合物 AMASTATIN
化合物 T22255
N-[(2S,3R)-3-氨基-2-羟基-5-甲基-1-氧代己基]-L-缬氨酰-L-缬氨酰-L-天冬氨酸
67655-94-1
Antipain (0.5 mg vial)
Amastatin (0.5 mg vial)
L-Aspartic acid, N-[(2S,3R)-3-amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl-L-valyl-
S-(R*,S*)]-N-[N-[N-(3-Amino-2-hydroxy-5-methyl-1-oxohexyl)-L-valyl]-L-valyl]-L-aspartic acid
s*))-(s-(r*
l-asparticacid,n-(n-(3-amino-2-hydroxy-5-methyl-1-oxohexyl)-l-valyl)-l-valyl)
N-[(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-L-VALYL-L-VALYL-L-ASPARTIC ACID
N-[(2S,3R)-3-Amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl-L-valyl-L-aspartic acid
Aids-059868
Aids059868
[(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-Val-val-Asp
N-[N-[N-[(2S,3R)-3-Amino-2-hydroxy-5-methyl-1-oxohexyl]-L-valyl]-L-valyl]-L-aspartic acid
N-[(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]-L-Val-L-Val-L-Asp-OH
(AMINO-2-HYDROXY-5-METHYL-HEXANOYL)-L-VALYL-L-VALYL-L-ASPARTIC ACID
AMASTATIN
AMASTATIN, STREPTOMYCES SPECIES
[(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-L-VALYL-L-VALYL-L-ASPARTIC ACID
(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL-VAL-VAL-ASP-OH