ChemicalBook > CAS DataBase List > IMISOPASEM MANGANESE
IMISOPASEM MANGANESE
IMISOPASEM MANGANESE
- CAS No.218791-21-0
- Chemical Name:IMISOPASEM MANGANESE
- CBNumber:CB41509117
- Molecular Formula:C21H35N5.Cl2Mn
- Formula Weight:483.387
- MOL File:218791-21-0.mol
IMISOPASEM MANGANESE Property
- storage temp. under inert gas (nitrogen or Argon) at 2-8°C
- solubility DMSO:5.0(Max Conc. mg/mL);10.34(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);41.38(Max Conc. mM)
PBS (pH 7.2):3.0(Max Conc. mg/mL);6.21(Max Conc. mM)
Water:16.0(Max Conc. mg/mL);33.1(Max Conc. mM) - form A crystalline solid
- color White to off-white
- FDA UNII 2Q6R3259KS
- NCI Drug Dictionary imisopasem manganese
Safety
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
IMISOPASEM MANGANESE Chemical Properties,Usage,Production
- Uses Relief of pain and inflammation.
-
in vivo
Imisopasem manganese is a small-molecule superoxide dismutase mimetic that has shown efficacy in animal model disease states in which superoxide anions are thought to play a key role. Imisopasem manganese inhibits the inflammatory response following the intrapleural injection of carrageenan in rats. All parameters of inflammation are attenuated by Imisopasem manganese except for NOx, PGE2 and IL-10 which remains unaltered[1]. Decreased apoptosis of the large and particularly the small bowel and marked recovery of both lymphoid and hematopoietic tissues occurs in the Imisopasem manganese pre-treated mice. Imisopasem manganese is effective in reducing TBI-induced tissue destruction and has potential as a new radioprotective agent[2].
IMISOPASEM MANGANESE Preparation Products And Raw materials
Raw materials
Preparation Products
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218791-21-0, IMISOPASEM MANGANESERelated Search:
- 抑制剂
- 伊米帕锰
- 218791-21-0
- Imisopasem manganese (M-40403, GC-4419)
- SC-72325
- SC72325
- SC 72325
- M40403; M 40403; M-40403; CG4419; CG 4419; CG-4419; SC72325; SC-72325; SC 72325; IMISOPASEM MANGANESE
- CG-4419
- CG4419
- CG 4419
- Imisopasem manganese(m40403)
- M-40403
- IMISOPASEM MANGANESE