Uses
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2-CHLORO-4-PHENYLQUINAZOLINE

Uses
2-CHLORO-4-PHENYLQUINAZOLINE Structure
2-CHLORO-4-PHENYLQUINAZOLINE
  • CAS No.29874-83-7
  • Chemical Name:2-CHLORO-4-PHENYLQUINAZOLINE
  • CBNumber:CB41490329
  • Molecular Formula:C14H9ClN2
  • Formula Weight:240.69
  • MOL File:29874-83-7.mol
2-CHLORO-4-PHENYLQUINAZOLINE Property
  • Melting point 113.0 to 117.0 °C
  • Boiling point 347.4±30.0 °C(Predicted)
  • Density 1.285±0.06 g/cm3(Predicted)
  • storage temp. under inert gas (nitrogen or Argon) at 2-8°C
  • form powder to crystal
  • pka 0.24±0.30(Predicted)
  • color White to Orange to Green
Safety
  • HS Code  :2933998090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P280-P305+P351+P338
2-CHLORO-4-PHENYLQUINAZOLINE Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: C3173
  • Product name : 2-Chloro-4-phenylquinazoline
  • Purity: min. 98.0 %
  • Packaging: 1G
  • Price: ₹7300
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: C3173
  • Product name : 2-Chloro-4-phenylquinazoline
  • Purity: min. 98.0 %
  • Packaging: 5G
  • Price: ₹19500
  • Updated: 2022/05/26
  • Buy: Buy

2-CHLORO-4-PHENYLQUINAZOLINE Chemical Properties,Usage,Production

  • Uses 2-Chloro-4-phenylquinazoline acts as a reagent in the synthesis of MTH1 inhibitors that are potential cancer eradicators.
  • Uses 2-CHLORO-4-PHENYLQUINAZOLINE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
  • Uses 2-Chloro-4-phenylquinazoline acts as a reagent in the synthesis of MTH1 inhibitors that are potential cancer eradicators.
  • Synthesis Synthesis_29874-83-7
    A 2 L flask was charged with 35.0 g (175.8 mmol) of 2,4-dichloroquinoline,22.5 g (184.6 mmol) of phenylboronic acid, 6.1 g (5.3 mmol) of tetrakis(triphenylphosphine)palladium(0) were added to 800 mL of tetrahydrofuran and 400 mL of water, and the mixture was heated to 60 ?? C for 12 hours under a nitrogen stream. . The resulting mixture was added to methanol (3000 mL), and the crystallized solid was filtered and dissolved in toluene, filtered through silica gel / celite, and the organic solvent was removed in an appropriate amount, and then recrystallization from methanol gave Intermediate I-A52-1 (36.8 g, 87% yield).
2-CHLORO-4-PHENYLQUINAZOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-CHLORO-4-PHENYLQUINAZOLINE Spectrum
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