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5-METHOXYURIDINE

5-METHOXYURIDINE Structure
5-METHOXYURIDINE
  • CAS No.35542-01-9
  • Chemical Name:5-METHOXYURIDINE
  • CBNumber:CB4144845
  • Molecular Formula:C10H14N2O7
  • Formula Weight:274.23
  • MOL File:35542-01-9.mol
5-METHOXYURIDINE Property
  • Density 1.65±0.1 g/cm3(Predicted)
  • storage temp. Sealed in dry,Store in freezer, under -20°C
  • pka 8?+-.0.10(Predicted)
  • form Solid
  • color White to off-white
  • λmax 279 (pH 2)；277 (pH 12)
Safety
  • WGK Germany  :3
  • HS Code  :29349990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

5-METHOXYURIDINE Chemical Properties,Usage,Production

  • Description 5-Methoxyuridine is an intermediate in the biosynthesis of pyrimidines and is also used as a precursor for other compounds. 5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist. It inhibits messenger RNA (mRNA) production in bacteria by interfering with sequence recognition and binding sites within the ribosome and preventing.
  • Chemical Properties Solid
  • Uses 5-Methoxyuridine is an analog of Uridine (U829910) and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.
  • Definition ChEBI: A derivative of uridine, bearing an additional methoxy substituent at position 5 on the uracil ring.
  • Synthesis 5-Hydroxyuridine was synthesized by the method described by T. Ueda. 5-Hydroxyuridine (30 mg) was further methylated by 20 y1 of dimethyl sulfate in 0.6 ml of 0.1 N NaOH. A reaction mixture was chromatographed on Whatman 3MM paper using solvent D. The band containing 5-Hydroxyuridine was extracted with water and the extract was further purified by paper chromatography in sol vent E. These procedures gave a 25% yield of mo5l). In addition to 5-Hydroxyuridine and the raw material, the methylated products contained 5% of 5-hydroxy-3-methyl uridine and 4% of 5-methoxy-3-methyluridine.
5-METHOXYURIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
5-METHOXYURIDINE Suppliers
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