ChemicalBook > CAS DataBase List > salvigenin

salvigenin

salvigenin Structure
salvigenin
  • CAS No.19103-54-9
  • Chemical Name:salvigenin
  • CBNumber:CB41375233
  • Molecular Formula:C18H16O6
  • Formula Weight:328.32
  • MOL File:19103-54-9.mol
salvigenin Property
  • Melting point 188 °C
  • Boiling point 535.9±50.0 °C(Predicted)
  • Density 1.314±0.06 g/cm3(Predicted)
  • storage temp. 4°C, protect from light
  • solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
  • form powder
  • pka 6.33±0.40(Predicted)
  • color Yellow
  • FDA UNII V522YCM28A
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319
  • Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

salvigenin Chemical Properties,Usage,Production

  • Uses Salvigenin is a neuroprotective agent used in the treatment of neurodegenerative diseases acting through oxidative stress on cells.
  • Definition ChEBI: Salvigenin is a trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups. It has a role as an autophagy inducer, an apoptosis inhibitor, an antilipemic drug, an immunomodulator, an antineoplastic agent, a neuroprotective agent, a hypoglycemic agent and a plant metabolite. It is a trimethoxyflavone and a monohydroxyflavone. It is functionally related to a scutellarein.
  • in vivo

    Salvigenin (0-9.68 μg/mouse/day; i.p.; 4 or 12 days) shows antitumor and immunomodulatory effects on tumor bearing mice[2].

    Animal Model:MCF-7 cell bearing inbred female Balb/c mice, aged from six to eight weeks[2]
    Dosage:3.65, 5.85 and 9.68 μg/mouse/day for four days or 12 days
    Administration:Intraperitoneal injection
    Result:Showed a significant increase in DTH response in a dose-dependent manner. Significantly decreased the rate of tumor growth, increased lymphocyte proliferation index, increased the level of IFN-γ and decreased IL-4 production. Exhibited a significant decrease of the splenic CD4+CD25+Foxp3+ T lymphocytes.
salvigenin Preparation Products And Raw materials
Raw materials
Preparation Products
salvigenin Suppliers
Global(105)Suppliers
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：factory@coreychem.com
  • Country：China
  • ProdList：29808
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Labnetwork lnc.
  • Tel：+86-27-50766799<br/>+8618062016861
  • Email：contact@labnetwork.com
  • Country：China
  • ProdList：19987
  • Advantage：58
salvigenin Spectrum
19103-54-9, salvigeninRelated Search:
  • Tetra-substituted Flavones
  • 黄酮类
  • 抑制剂
  • 对照品
  • 黄酮
  • 对照品
  • 植物提取物
  • 标准品
  • 三裂鼠尾草素,10 MM DMSO 溶液
  • 5-羟基-6,7-二甲氧基-2-(4-甲氧基苯基)-4H-苯并吡喃-4-酮
  • 鼠尾草素
  • 三裂尾草素(供应商少)
  • 三裂尾草素
  • 三裂鼠尾草素
  • 19103-54-9
  • Salvigenin, 10 mM in DMSO
  • Salvigenin Salvigenin
  • Salvigenin,inhibit,Apoptosis,immunomodulatory,ROS Kinase,Autophagy,Inhibitor,neuroprotective,antioxidant
  • 5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)chromen-4-one
  • 4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-
  • 5-Hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Home

My