ChemicalBook > CAS DataBase List > 2-Iodophenylacetic acid

2-Iodophenylacetic acid

CAS No.18698-96-9
Chemical Name:2-Iodophenylacetic acid
CBNumber:CB4131159
Molecular Formula:C8H7IO2
Formula Weight:262.04
MOL File:18698-96-9.mol

2-Iodophenylacetic acid Property

Melting point 116-119 °C (lit.)
Boiling point 344.5±17.0 °C(Predicted)
Density 1.885±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Powder
pka pK1:4.038 (25°C)
color Cream
Sensitive Light Sensitive
BRN 2086800
CAS DataBase Reference 18698-96-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :26-36-37
WGK Germany :3
Hazard Note :Irritant/Light Sensitive
HazardClass :IRRITANT, LIGHT SENSITIVE
HS Code :29163990

NFPA 704:

	1
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319-H335
Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338

2-Iodophenylacetic acid Price More Price(4)

Brand: ALFA India
Product number: ALF-L15116-06
Product name : 2-Iodophenylacetic acid, 98+%
Purity:
Packaging: 5g
Price: ₹6004
Updated: 2022/05/26
Buy: Buy

Brand: ALFA India
Product number: ALF-L15116-03
Product name : 2-Iodophenylacetic acid, 98+%
Purity:
Packaging: 1g
Price: ₹1586
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: I0723
Product name : 2-Iodophenylacetic Acid
Purity: min. 97.0 %
Packaging: 5G
Price: ₹6000
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: I0723
Product name : 2-Iodophenylacetic Acid
Purity: min. 97.0 %
Packaging: 25G
Price: ₹20700
Updated: 2022/05/26
Buy: Buy

2-Iodophenylacetic acid Chemical Properties,Usage,Production

Chemical Properties Cream powder
Application 2-Iodophenylacetic acid may be used in the preparation of:
2-iodophenylacetyl chloride
3,4-dimethoxyphenyl 2-iodophenylacetate
N-{2-[2-(2-iodophenyl)-acetylamino]-ethyl}-2-(3,4- dichlorophenyl)-acetamide
Uses 2-Iodophenylacetic acid is a synthetic intermediate that is widely used in the chemical, pharmaceutical and cosmetic industries. 2-Iodophenylacetic acid is also used as a reagent to synthesize Cepharanone B, a natural and potentially antineoplastic aristolactam that is found in Piper longum (a medicinal plant native to India).
Preparation synthesis of 2-Iodophenylacetic acid: The anthranilic acid solution was acidified with sulfuric acid to pH = 1 followed by a diazotization reaction. The diazonium was added dropwise to the potassium iodide-sulfuric acid solution (3.5 g KI, 1.0 mL concentrated H2SO4, 5 mL water) preheated to 60-70 °C, stirred for 30 min, placed overnight, and filtered to obtain the product. Recrystallization with 50% ethanol aqueous solution gave 3.83 g of 2-iodophenylacetic acid, the yield was 73% (calculated as o-nitrophenylacetic acid), and the melting point was 113-115 °C (117 °C reported in the literature).
General Description 2-Iodophenylacetic acid is a substituted acetic acid that can be prepared from 2-iodobenzyl cyanide. It undergoes palladium-catalyzed reaction with allenes to form 1,3-butadienes. 2-Iodophenylacetic acid also undergoes photolysis in carbon tetrachloride to form the corresponding chloro compound.