excisanin A
- Product Nameexcisanin A
- CAS78536-37-5
- CBNumberCB41308495
- MFC20H30O5
- MW350.45
- MDL NumberMFCD32644906
- MOL File78536-37-5.mol
Chemical Properties
| Boiling point: | 558.719±50.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.301±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pka | 12.784±0.70(predicted) |
excisanin A Chemical Properties,Usage,Production
Description
Excisanin A is a diterpenoid compound purified from Isodon macrocalyxin D that has anti-cancer properties with little toxicity.Uses
Excisanin A is a potent anticancer agent. Excisanin A inhibits cell proliferation, migration, adhesion and invasion. Excisanin A decreases the expression of MMP-2, MMP-9, p-FAK, p-Src, integrin β1 protein. Excisanin A has the potential for the research of breast cancer[1].References
[1] Qin J, et al. A diterpenoid compound, excisanin A, inhibits the invasive behavior of breast cancer cells by modulating the integrin β1/FAK/PI3K/AKT/β-catenin signaling. Life Sci. 2013 Nov 4;93(18-19):655-63. DOI:10.1016/j.lfs.2013.09.002excisanin A Suppliers
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