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KRIBB 3

KRIBB 3 Structure
KRIBB 3
  • CAS No.129414-88-6
  • Chemical Name:KRIBB 3
  • CBNumber:CB3972401
  • Molecular Formula:C19H19NO4
  • Formula Weight:325.36
  • MOL File:129414-88-6.mol
KRIBB 3 Property
  • Melting point 147-148 °C
  • Boiling point 467.5±45.0 °C(Predicted)
  • Density 1.181±0.06 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility DMSO: 25 mM
  • form A solid
  • pka 8.51±0.48(Predicted)
Safety
  • Hazard Codes  :Xn
  • Risk Statements  :22
  • RIDADR  :UN 2811 6.1/PG 3
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301-H413
  • Precautionary statements P264-P270-P301+P310-P321-P330-P405-P501

KRIBB 3 Chemical Properties,Usage,Production

  • Uses Kribb3 is an inhibitor for microtubule. KRIBB3 inhibits the proliferation of cancer cells with GI50 of 0.2-2.5 μM, arrests cell cycle at G2/M phase, and induces apoptosis in HCT-116. Kribb3 exhibits antitumor activity in mouse models[1].
  • References [1] Shin KD, et al., KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells. Biochem Pharmacol. 2008 Jan 15;75(2):383-94. DOI:10.1016/j.bcp.2007.08.027
KRIBB 3 Preparation Products And Raw materials
Raw materials
Preparation Products
KRIBB 3 Suppliers
Global(20)Suppliers
  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
  • ProdList：52924
  • Advantage：58
  • Supplier： DC Chemicals
  • Tel：021-58447131<br/>13564518121
  • Email：sales@dcchemicals.com
  • Country：China
  • ProdList：9409
  • Advantage：58
  • Supplier： Energy Chemical
  • Tel：021-58432009<br/>400-005-6266
  • Email：marketing1@energy-chemical.com
  • Country：China
  • ProdList：44814
  • Advantage：58
  • Supplier： TargetMol Chemicals Inc.
  • Tel： 4008200310
  • Email：marketing@tsbiochem.com
  • Country：China
  • ProdList：24719
  • Advantage：58
  • Supplier： Cayman Chemical Company
  • Tel：800-364-9897
  • Email：sales@caymanchem.com
  • Country：China
  • ProdList：27736
  • Advantage：58
KRIBB 3 Spectrum
129414-88-6, KRIBB 3Related Search:
  • 抑制剂
  • KRIBB3 (5-(5-ETHYL-2-HYDROXY-4-METHOXYPHENYL)-4-(4-METHOXYPHENYL)ISOXAZOLE),HSP27抑制剂
  • 化合物 KRIBB3
  • 4-乙基-5-甲氧基-2-[4-(4-甲氧基苯基)-5-异恶唑基]苯酚
  • 129414-88-6
  • KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole), Hsp27 inhibitor
  • 4-Ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]phenol
  • Phenol, 4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-
  • 4-ethyl-3-methoxy-6-[4-(4-methoxyphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone
  • KRIBB3 (5-(5-Ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)isoxazole)

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