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piperylone

piperylone Structure
piperylone
  • CAS No.2531-04-6
  • Chemical Name:piperylone
  • CBNumber:CB3941405
  • Molecular Formula:C17H23N3O
  • Formula Weight:285.38
  • MOL File:2531-04-6.mol
piperylone Property
  • Boiling point 413.0±55.0 °C(Predicted)
  • Density 1.121±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility Soluble in DMSO
  • pka pK1 5.90; pK2 9.15(at 25℃)
  • FDA UNII XWH5VH1L2F
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

piperylone Chemical Properties,Usage,Production

  • Originator Palerol, Novartis
  • Uses Piperylone can be used as an antispasmodic.
  • Manufacturing Process A mixture of 8.8 parts of α-ethylbenzoylacetic acid ethyl ester and 5,3 parts of N-methyl-piperidyl-4-hydrazine is allowed to stand for 30 min at 22°C, after which the mixture is heated for 5 hours to 130°C under a pressure of 12 mm. After 4 hours 1-(N-methylpiperidyl-4)-3-phenyl-4-ethylpyrazolone-5 begins crystallize out. The reaction mixture is allowed to cool, after which the crystal mass is triturated with ether and then recrystallized from methanol-ether or from acetone. Melting point 159-161°C.
  • Therapeutic Function Analgesic
  • References [1] Martínková J, et al. A study of the inhibition of adrenaline-induced vasoconstriction in the isolated perfused liver of rabbit. Hepatology. 1990 Nov;12(5):1157-65. DOI:10.1002/hep.1840120514
piperylone Preparation Products And Raw materials
Raw materials
Preparation Products
piperylone Suppliers
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piperylone Spectrum
2531-04-6, piperyloneRelated Search:
  • 抑制剂
  • 哌立酮
  • 2531-04-6
  • 3H-Pyrazol-3-one, 4-ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl-
  • PR66
  • 4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1H-pyrazol-3-one
  • 4-ethyl-2-(1-methyl-4-piperidyl)-5-phenyl-1H-pyrazol-3-one
  • 4-Ethyl-1,2-dihydro-2-(1-methylpiperidin-4-yl)-5-phenyl-3H-pyrazol-3-one
  • Piperylonum
  • piperylone

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