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EB-47

EB-47 Structure
EB-47
  • CAS No.366454-36-6
  • Chemical Name:EB-47
  • CBNumber:CB3769005
  • Molecular Formula:C24H27N9O6
  • Formula Weight:537.53
  • MOL File:Mol file
EB-47 Property
  • Density 1.83±0.1 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility H2O: 10 mg/mL, soluble
  • form solid
  • pka 12.99±0.70(Predicted)
  • color white
  • Water Solubility water: 50mg/mL
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

EB-47 Chemical Properties,Usage,Production

  • Uses EB 47 is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Poly(ADP-ribose) polymerases (PARPs) play a major role in cellular survival and maintenance of energy stores after genotoxic insult.
  • Biological Activity Cell permeable: yes', 'Primary Target
    PARP-1', 'Product does not compete with ATP.', 'Reversible: no
  • in vivo

    EB-47 (2 μM; 5 days) decreases the number of embryo implantation sites and blastocysts at day 5. PARP1 participates in the process of embryo implantation[3].

  • IC 50 ARTD1/PARP1: 45 nM (IC50)
EB-47 Preparation Products And Raw materials
Raw materials
Preparation Products
EB-47 Suppliers
Global(37)Suppliers
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
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  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
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  • Supplier：
    NewCan Biotech Limited
  • Tel：+86-0571-86912261<br/>+8613735419629
  • Email：sales@newcanbio.com
  • Country：China
  • ProdList：9985
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  • Supplier：
    TargetMol Chemicals Inc.
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  • Email：support@targetmol.com
  • Country：United States
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  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
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  • Supplier： J & K SCIENTIFIC LTD.
  • Tel： 18210857532
  • Email：jkinfo@jkchemical.com
  • Country：China
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  • Supplier： BOC Sciences
  • Tel： 16314854226
  • Email：inquiry@bocsci.com
  • Country：United States
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  • Supplier： Energy Chemical
  • Tel：021-58432009<br/>400-005-6266
  • Email：marketing@energy-chemical.com
  • Country：China
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EB-47 Spectrum
  • P to
  • Enzyme Inhibitors by Enzyme
  • PARP Poly(ADP-ribose) Polymerase
  • 抑制剂
  • BioChemical
  • Biochemicals and Reagents
  • PARP Poly(ADP-ribose) Polymerase
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • P to Q
  • C24H29N9O6Cl2
  • 化合物EB-47,10 MM DMSO 溶液
  • 化合物EB-47
  • 化合物 T11143
  • 366454-36-6
  • EB-47, 10 mM in DMSO
  • Adenosine, 5'-deoxy-5'-[4-[2-[(2,3-dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxo-
  • PARP Inhibitor IX, EB-47
  • EB 47 DIHYDROCHLORIDE
  • 5'-Deoxy-5'-[4-[2-[(2,3-dihydro-1-oxo-1H-isoindol-4-yl)aMino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosine Dihydrochloride
  • 4-[1-(6-AMino-9H-purin-9-yl)-1-deoxy-β-D- ribofuranuronoyl]-N-(2,3-dihydro-1-oxo-1H-isoindol-4-yl)-1-piperazineacetaMide Dihydrochloride
  • EB-47

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