Chemical Properties
Off-white powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Imperata cylindrica, reed rhizome, seed kernel and root of Coix lacryma.
Uses
6-Methoxybenzoxazolinone is an intermdiate in the synthesis of DIMBOA-4-O-β-D-glucuronide which is a metabolite of DIMBOA which acts as an antifungal and antialgal agent in crops. The benzoxazinone group within the structure allows for these effects.
Definition
ChEBI: Coixol is a benzoxazole.
General Description
6-Methoxy-2-benzoxazolinone (MBOA) is obtained by reacting 2-amino-5-methoxyphenol hydrochloride with urea. MOBA is a naturally occurring auxin-inhibiting substance present in maize shoots.
in vivo
| Animal Model: | 9–12 weeks, Sprague Dawley (SD) male rats[3] |
| Dosage: | 25, 50 mg/kg |
| Administration: | P.o. |
| Result: | Decreased the blood glucose levels significantly, improved glucose tolerance. |
