ChemicalBook > CAS DataBase List > BISNORCHOLENALDEHYDE
BISNORCHOLENALDEHYDE
BISNORCHOLENALDEHYDE
BISNORCHOLENALDEHYDE Property
- Melting point 159-160 °C
- Boiling point 459.4±14.0 °C(Predicted)
- Density 1.07±0.1 g/cm3(Predicted)
- solubility Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
- form Solid
- color White to Off-White
-
Symbol(GHS)
- Signal wordDanger
- Hazard statements H351-H362-H360
- Precautionary statements P201-P202-P281-P308+P313-P405-P501-P201-P260-P263-P264-P270-P308+P313
BISNORCHOLENALDEHYDE Chemical Properties,Usage,Production
- Description Androstenedione is the main product after phytosterol fermentation by Mycobacteria. Bisnorcholenaldehyde (BA; 3-Oxopregn-4-ene-20-carboxaldehyde) is one of the by-products produced during fermentation. Bisnorcholenaldehyde is an essential intermediate in the production of progesterone, which is used to treat threatened abortion or habitual abortion disease caused by luteal insufficiency. It is a precursor of androgen, estrogen, glucocorticoid and intermediates of steroid hormone synthesis[1]. In addition, BA is used in magnetic-based graphene composites with steroidal diamine dimer as a potential drug in hyperthermia cancer therapy.
- Uses Bisnorcholenaldehyde is hydrocarbon derivatives and can be used as reference materials for medical impurities.
- Toxics Screening Level The initial threshold screening level (ITSL) for progesterone 4 is 0.04 μg/m3 based on an annual averaging time.
- References [1] Shi-Dong Xu. “Refining androstenedione and bisnorcholenaldehyde from mother liquor of phytosterol fermentation using macroporous resin column chromatography followed by crystallization.” Journal of Chromatography B 1079 (2018): Pages 9-14.
BISNORCHOLENALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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3986-89-8, BISNORCHOLENALDEHYDERelated Search:
- 20α-Acetoxy-4-pregnen-3-one (17α)-Pregn-4-ene-3,20-dione 4-PREGNEN-20-ALPHA-OL-3-ONE 4,9(11)-PREGNADIEN-3,20-DIONE 4-PREGNEN-20-BETA-OL-3-ONE 1,4-PREGNADIEN-3,20-DIONE Progesterone EP Impurity G Progesterone EP Impurity F Benzene, 2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro 21ξ-morpholino-23,24-dinor-chola-4,20-dien-3-one Androstenone hydrazone 17-Iodoandrosta-5,16-dien-3beta-ol tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate CarbaMic acid, [(2R)-2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethyl]-, 1,1-diMethylethyl ester 2-Oxazolidinone, 5-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-, (5R)- N-(1-Cyclohexen-1-yl)morpholine Abiraterone Pregna-4,6-diene-3,20-dione
- 标准品
- 杂质-黄体酮杂质
- 杂质对照品
- 黄体酮EP杂质 I-02
- 双降胆醛
- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-二甲基-3-氧代-2,3,6,7,8,9,10,11,12,13,14,15,16,17-十四氢-1H-环戊基[A]菲-17-基)丙醛 (孕酮杂质)
- 黄体酮 EP 杂质 I(S 异构体)
- 黄体酮杂质23
- 黄体酮杂质EP I
- 黄体酮杂质24
- 孕酮EP杂质I
- 孕酮杂质7
- 孕酮EP杂质I(S-异构体)
- 孕酮杂质I (EP/BP)
- 黄体酮杂质I (EP/BP)
- 3986-89-8
- (2S)-2-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal
- (2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]propanal
- Didroprogesterone impurity 2
- Progesterone Impurity(S-Isomer)
- Progesterone EP Impurity I-02
- Bisnorcholenaldehyde
- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal (Progesterone Impurity)
- (20S)-20-Formylpregn-4-en-3-one
- Progesterone Impurity 24
- 3-Oxo-pregn-4-ene-20α- carboxaldehyde
- (S)-2-((8S,9S,10R,13S,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)propanal
- Pregn-4-ene-20-carboxaldehyde, 3-oxo-, (20S)-
- Bisnorcholeldehyde
- BNKY018-PG01
- (20S)-3-oxopregn-4-ene-20-carboxaldehyde
- Progesterone EP Impurity I (S-isomer)
- Progesterone Impurity 7
- Progesterone EP Impurity I
- 4-PREGNEN-3-ONE-20-BETA-CARBOXALDEHYDE
- 4-PREGNEN-20BETA-CARBOXALDEHYDE-3-ONE
- 3-KETO-4-PREGNENE-20-BETA-CARBOXALDEHYDE
- KETOBISNORALDEHYDE