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IDRA 21

IDRA 21 Structure
IDRA 21
  • CAS No.22503-72-6
  • Chemical Name:IDRA 21
  • CBNumber:CB3468324
  • Molecular Formula:C8H9ClN2O2S
  • Formula Weight:232.69
  • MOL File:22503-72-6.mol
IDRA 21 Property
  • Melting point 209 °C(Solv: acetic acid (64-19-7))
  • Boiling point 405.1±55.0 °C(Predicted)
  • Density 1.394±0.06 g/cm3(Predicted)
  • storage temp. Keep in dark place,Inert atmosphere,Room temperature
  • solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
  • form Solid
  • pka 9.78±0.40(Predicted)
  • color Off-White to Pale Yellow
  • InChI InChI=1S/C8H9ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-5,10-11H,1H3
  • InChIKey VZRNTCHTJRLTMU-UHFFFAOYSA-N
  • SMILES S1(=O)(=O)C2=CC(Cl)=CC=C2NC(C)N1
  • FDA UNII 689UW7PT68
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • Safety Statements  :24/25
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P280-P305+P351+P338
IDRA 21 Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: I5773
  • Product name : IDRA 21
  • Purity: ≥98%
  • Packaging: 5MG
  • Price: ₹24183.05
  • Updated: 2022/06/14
  • Buy: Buy

IDRA 21 Chemical Properties,Usage,Production

  • Chemical Properties white to off-white crystalline powder
  • Uses IDRA-21 is a benzothiadiazine derivative and a positive allosteric modulator of glutamate AMPA receptors (1,2,3,4). It is able to increase excitatory synaptic strength by inhibiting AMPA receptor desensitization. IDRA 21 may exhibit therapeutic effects to ameliorate memory deficits in patients with cognitive impairments such as Alzheimer''s disease.
  • Uses IDRA-21 inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).
  • Definition ChEBI: 7-chloro-3-methyl-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide is a benzothiadiazine.
  • Biological Activity Inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. More able to cross the blood-brain barrier than cyclothiazide (6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide ).
  • storage Room temperature
IDRA 21 Preparation Products And Raw materials
Raw materials
Preparation Products
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IDRA 21 Spectrum
22503-72-6, IDRA 21Related Search:
  • API
  • 抑制剂
  • 高端化学
  • 神经心脑血管系列
  • 产品
  • 其它
  • 化合物
  • 医药原料
  • 保健品添加剂
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Ionotropic Glutamate Receptor Modulators
  • Ion Channels
  • Ligand-Gated Ion Channels
  • IDRA21/IDRA-21药辅级99%
  • 化合物IDRA-21,10 MM DMSO 溶液
  • IDRA21/IDRA-21 药辅
  • 化合物IDRA-21
  • IDRA 21 7-氯-3-甲基-3,4-二氢-2H-1,2,4-苯并噻二嗪 1,1-二氧化物
  • 7-氯-3-甲基-3,4-二氢-2H-1,2,4-苯并噻二嗪 1,1-二氧化物IDRA 21
  • 7-氯-3-甲基-3,4-二氢-2H-1,2,4-苯并噻二嗪 1,1-二氧化物
  • 7-氯-3,4-二氢-3-甲基-2H-1,2,4-苯并噻二嗪 1,1-二氧化物
  • 22503-72-6
  • IDRA-21, 10 mM in DMSO
  • DRA 21
  • S-18986 IDRA-21 AMPAKINE
  • AMPAKINE
  • IDRA 21 Benzothiadiazine,7-chloro- 3,4-dihydro-3-methyl-,1,1- dioxide
  • 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-...
  • IDRA 21,7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazineS,S-dioxide
  • 2H-1,2,4-Benzothiadiazine,7-chloro-3,4-dihydro-3-Methyl-, 1,1-dioxide
  • 7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
  • 7-chloro-3-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
  • IDRA 21,98%
  • 7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE
  • 7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE
  • 7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE
  • IDRA 21

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