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VALERENIC ACID

VALERENIC ACID Structure
VALERENIC ACID
  • CAS No.3569-10-6
  • Chemical Name:VALERENIC ACID
  • CBNumber:CB3449648
  • Molecular Formula:C15H22O2
  • Formula Weight:234.33
  • MOL File:3569-10-6.mol
VALERENIC ACID Property
  • Melting point 134-139°C
  • Boiling point 374.5±21.0 °C(Predicted)
  • Density 1.06±0.1 g/cm3(Predicted)
  • storage temp. −20°C
  • solubility Chloroform (Slightly), Ethanol (Slightly),Methanol (Slightly)
  • pka 4.88±0.19(Predicted)
  • form Solid
  • color White to Off-White
  • BRN 3138020
  • LogP 5.188 (est)
  • CAS DataBase Reference 3569-10-6(CAS DataBase Reference)
  • FDA UNII 34NDB285PM
  • UNSPSC Code 85151701
  • NACRES NA.24
Safety
  • WGK Germany  :3
  • RTECS  :UD3357700
  • F  :8-10
  • HS Code  :2916205000
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
VALERENIC ACID Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: 51964
  • Product name : Valerenic acid
  • Purity: analytical standard
  • Packaging: 1MG
  • Price: ₹7263.58
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 51964
  • Product name : Valerenic acid
  • Purity: analytical standard
  • Packaging: 5MG
  • Price: ₹29909.48
  • Updated: 2022/06/14
  • Buy: Buy

VALERENIC ACID Chemical Properties,Usage,Production

  • Uses Valerenic Acid, acts as a subtype-selective GABAA receptor agonist in neonatal rat brainstem preparations. It can be used for the synthesis of Valerena-4,7(11)-diene, a highly active sedative.
  • Definition ChEBI: A monocarboxylic acid that is 2-methylprop-2-enoic acid which is substituted at position 3 by a 3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl group. A bicyclic sesquiterpenoid constituent of the essential oil of the Valerian plant.
  • Biological Activity Positive allosteric modulator of GABA A receptors that displays preference for receptors containing β 2 or β 3 subunits. Directly activates the receptor and also blocks the channel at high concentrations. Displays a sedative and anxiolytic activity in vivo . Also acts as a partial? agonist of 5-HT 5A receptors.
  • in vivo

    Valerenic acid (1-6 mg/kg i.p. or 10 mg/kg p.o.) decreases the aversion of wild type mice to the lit area[2].
    Valerenic acid (10 mg/kg; p.o.) increases the proportion of time 129X1/SvJ mice spent onto the open arms[2].

  • IC 50 GABAA; 5-HT5A Receptor: 17.2 μM (IC50)
VALERENIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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VALERENIC ACID Spectrum
3569-10-6, VALERENIC ACIDRelated Search:
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  • (-)-VALERENIC ACID
  • 缬草标准化干浸膏 EP标准品
  • (2E)-3-[(4S,7R,7AR)-2,4,5,6,7,7A-六氢-3,7-二甲基-1H-茚-4-基]-2-甲基-2-丙烯酸
  • 缬草烯酸
  • 缬草素
  • 3569-10-6
  • Valerenic Acid (1707908)
  • VALERENIC ACID USP/EP/BP
  • Valerian dry extract HRS
  • Valerenic acid - Valeriana officinalis (common valerian)
  • 2-Propenoic acid,3-[(4S,7R,7aR)-2,4,5,6,7,7a-hexahydro-3,7-diMethyl-1H-inden-4-yl]-2-Methyl-,(2E)-
  • VALERENIC ACID(P)(AHP Verified)
  • Valerenic aci
  • VALERENIC ACID(AHP)
  • VALERENIC ACID SNAP-N-SHOOT 0.1mg/mL(P)
  • VALERENIC ACID(P)
  • Valerenic Acid (15 mg)
  • 2-Propenoic acid, 3-(2,4,5,6,7,7A-hexahydro-3,7-dimethyl-1H-inden-4-yl)-2-methyl-, (4S-(4alpha(E),7beta,7aalpha))-
  • (2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-Hexadydro-3,7-dimethyl-1H-inden-4-yl]-2-methyl-2-propenoic acid
  • (E)-3-[(4S)-2,4,5,6,7,7aα-Hexahydro-3,7β-dimethyl-1H-inden-4-yl]-2-methylpropenoic acid
  • VALERENIC ACID WITH HPLC
  • VALERENIC ACID