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VALERENIC ACID
VALERENIC ACID
- CAS No.3569-10-6
- Chemical Name:VALERENIC ACID
- CBNumber:CB3449648
- Molecular Formula:C15H22O2
- Formula Weight:234.33
- MOL File:3569-10-6.mol
VALERENIC ACID Property
- Melting point 134-139°C
- Boiling point 374.5±21.0 °C(Predicted)
- Density 1.06±0.1 g/cm3(Predicted)
- storage temp. −20°C
- solubility Chloroform (Slightly), Ethanol (Slightly),Methanol (Slightly)
- pka 4.88±0.19(Predicted)
- form Solid
- color White to Off-White
- BRN 3138020
- LogP 5.188 (est)
- CAS DataBase Reference 3569-10-6(CAS DataBase Reference)
- FDA UNII 34NDB285PM
- UNSPSC Code 85151701
- NACRES NA.24
Safety
- WGK Germany :3
- RTECS :UD3357700
- F :8-10
- HS Code :2916205000
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
VALERENIC ACID Price
More Price(2)
- Brand: Sigma-Aldrich(India)
- Product number: 51964
- Product name : Valerenic acid
- Purity: analytical standard
- Packaging: 1MG
- Price: ₹7263.58
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 51964
- Product name : Valerenic acid
- Purity: analytical standard
- Packaging: 5MG
- Price: ₹29909.48
- Updated: 2022/06/14
- Buy: Buy
VALERENIC ACID Chemical Properties,Usage,Production
- Uses Valerenic Acid, acts as a subtype-selective GABAA receptor agonist in neonatal rat brainstem preparations. It can be used for the synthesis of Valerena-4,7(11)-diene, a highly active sedative.
- Definition ChEBI: A monocarboxylic acid that is 2-methylprop-2-enoic acid which is substituted at position 3 by a 3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl group. A bicyclic sesquiterpenoid constituent of the essential oil of the Valerian plant.
- Biological Activity Positive allosteric modulator of GABA A receptors that displays preference for receptors containing β 2 or β 3 subunits. Directly activates the receptor and also blocks the channel at high concentrations. Displays a sedative and anxiolytic activity in vivo . Also acts as a partial? agonist of 5-HT 5A receptors.
-
in vivo
Valerenic acid (1-6 mg/kg i.p. or 10 mg/kg p.o.) decreases the aversion of wild type mice to the lit area[2].
Valerenic acid (10 mg/kg; p.o.) increases the proportion of time 129X1/SvJ mice spent onto the open arms[2]. - IC 50 GABAA; 5-HT5A Receptor: 17.2 μM (IC50)
VALERENIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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3569-10-6, VALERENIC ACIDRelated Search:
- Elderberry Cornmint oil VALERENIC ACID USP(CRM STANDARD) VALERENIC ACID SNAP-N-SHOOT 0.1MG/ML(SECONDARY STANDARD) VALERENIC ACID(AMERICAN HERBAL PHARMACOPOEIA) VALERIAN ROOT EXTRACT / VALERENIC ACID Didrovaltratum (2E)-3-CYCLOHEXYLPROP-2-ENOIC ACID VALENERAL ACETOXYVALERENIC ACID 2,4-DIMETHYL-2-PENTENOIC ACID 1-ETHYL-2-METHYLCYCLOPENTENE 1-BUTYLCYCLOPENTENE VALERENIC ACID 1-ISO-PROPYLCYCLOPENTENE 1,2,3-TRIMETHYLCYCLOPENTENE
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- (-)-VALERENIC ACID
- 缬草标准化干浸膏 EP标准品
- (2E)-3-[(4S,7R,7AR)-2,4,5,6,7,7A-六氢-3,7-二甲基-1H-茚-4-基]-2-甲基-2-丙烯酸
- 缬草烯酸
- 缬草素
- 3569-10-6
- Valerenic Acid (1707908)
- VALERENIC ACID USP/EP/BP
- Valerian dry extract HRS
- Valerenic acid - Valeriana officinalis (common valerian)
- 2-Propenoic acid,3-[(4S,7R,7aR)-2,4,5,6,7,7a-hexahydro-3,7-diMethyl-1H-inden-4-yl]-2-Methyl-,(2E)-
- VALERENIC ACID(P)(AHP Verified)
- Valerenic aci
- VALERENIC ACID(AHP)
- VALERENIC ACID SNAP-N-SHOOT 0.1mg/mL(P)
- VALERENIC ACID(P)
- Valerenic Acid (15 mg)
- 2-Propenoic acid, 3-(2,4,5,6,7,7A-hexahydro-3,7-dimethyl-1H-inden-4-yl)-2-methyl-, (4S-(4alpha(E),7beta,7aalpha))-
- (2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-Hexadydro-3,7-dimethyl-1H-inden-4-yl]-2-methyl-2-propenoic acid
- (E)-3-[(4S)-2,4,5,6,7,7aα-Hexahydro-3,7β-dimethyl-1H-inden-4-yl]-2-methylpropenoic acid
- VALERENIC ACID WITH HPLC
- VALERENIC ACID