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LUPENONE

LUPENONE Structure
LUPENONE
  • CAS No.1617-70-5
  • Chemical Name:LUPENONE
  • CBNumber:CB3447619
  • Molecular Formula:C30H48O
  • Formula Weight:424.7
  • MOL File:1617-70-5.mol
LUPENONE Property
  • Melting point 165-167°C
  • Boiling point 485.7±14.0 °C(Predicted)
  • Density 1.115 g/cm3(Temp: 18 °C)
  • storage temp. -20°C Freezer
  • solubility Chloroform (Slightly), Methanol (Slightly)
  • form Solid
  • color White
  • LogP 10.400 (est)
Safety
  • Hazard Codes  :Xi
  • HS Code  :29142990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P305+P351+P338

LUPENONE Chemical Properties,Usage,Production

  • Uses Lupenone is a lupane triterpenoid with antioxidant and anticholinesterase activity. It also a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor.
  • Definition ChEBI: A natural product found in Cupania cinerea.
  • in vivo

    Lupenone (6, 12, 24 mg/kg/day, gavage for 6 weeks) improves type 2 diabetic nephropathy by regulating NF-κB pathway-mediated inflammation and TGF-β1/Smad/ CTGF-related fibrosis[2].

    Animal Model:Spontaneous type 2 diabetic nephropathy db/db mouse models[1]
    Dosage:6, 12, 24 mg/kg
    Administration:i.g.
    Result:Maintained the fasting blood glucose.
    Reduced glycosylated hemoglobin, insulin, and 24 h proteinuria levels.
    Regulated changes in biochemical indicators
  • IC 50 Trypanosoma
LUPENONE Preparation Products And Raw materials
Raw materials
Preparation Products
LUPENONE Suppliers
Global(118)Suppliers
  • Supplier：
    career henan chemical co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：sales@coreychem.com
  • Country：China
  • ProdList：29859
  • Advantage：58
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
  • Country：United States
  • ProdList：19552
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
LUPENONE Spectrum
1617-70-5, LUPENONERelated Search:
  • Building block
  • 中药标准品，对照品
  • 抑制剂
  • 高端化学
  • 标准品，对照品
  • 标准品 -中药标准品
  • 三萜
  • 对照品-中药对照品
  • 对照品
  • 标准品-对照品
  • 对照品
  • 标准品
  • 植物提取物
  • 1657-70-5
  • 羽扇烯酮/萜类
  • (1R,3AR,5AR,5BR,7AR,11AR,11BR,13AR,13BR)-3A,5A,5B,8,8,11A-六甲基-1-(丙烯-2-基)二十氢-9H-环戊烷[A]苯并菲-9-酮
  • 羽扇豆烯酮
  • 羽扇烯酮
  • 1617-70-5
  • (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one
  • (1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-2,3,4,5,6,7,7a,10,11,11b,12,13,13a,13b-tetradecahydro-1H-cyclopenta[a]chrysen-9-one
  • Aids082905
  • (1R,3Ar,4S,5ar,5br,7ar,11ar,11br,13ar,13br)-1-isopropenyl-3A,5A,5B,8,8,11A-hexamethyl-eicosahydro-cyclopenta[A]chrysen-9-one
  • Lupa-20(30)-ene-3-one
  • Lupa-20(29)-ene-3β-one
  • Lup-20(29)-en-3-one
  • 5α-Lup-20(29)-en-3-one
  • LUPENONE(RG)
  • Lup-20(29)
  • -en-3-one
  • 18-LUPEN-3-ONE
  • LUPENONE
  • Aids-082905

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