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BAPTA

BAPTA Structure
BAPTA
  • CAS No.85233-19-8
  • Chemical Name:BAPTA
  • CBNumber:CB3406887
  • Molecular Formula:C22H24N2O10
  • Formula Weight:476.43
  • MOL File:85233-19-8.mol
BAPTA Property
  • Melting point 177-179 °C
  • Boiling point 575.89°C (rough estimate)
  • Density 1.4482 (rough estimate)
  • refractive index 1.6500 (estimate)
  • RTECS MC0423000
  • storage temp. 2-8°C
  • solubility Soluble in dimethyl sulfoxide
  • form Powder
  • pka 1.40±0.10(Predicted)
  • color White to off-white
  • Water Solubility Soluble in water and sodium bicarbonate.
  • λmax 209 nm, 254 nm, 203 nm, 274 nm
  • Merck 14,957
  • BRN 5192406
  • Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
  • Biological Applications Calcium indicators; zinc indicators; treating acute cell death,cerebral infarction,myocardial infarction,hepatonecrosis,kidney ischemic necrosis,necrotizing pancreatitis,amyloidosis,atherosclerosis,diseases characteriz
  • InChIKey FTEDXVNDVHYDQW-UHFFFAOYSA-N
  • CAS DataBase Reference 85233-19-8(CAS DataBase Reference)
  • FDA UNII K22DDW77C0
  • UNSPSC Code 12352112
  • NACRES NA.23
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
BAPTA Price More Price(11)
  • Brand: Sigma-Aldrich(India)
  • Product number: A4926
  • Product name : 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
  • Purity: 98%
  • Packaging: 250MG
  • Price: ₹9655.9
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: A4926
  • Product name : 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
  • Purity: 98%
  • Packaging: 1G
  • Price: ₹12990
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: A4926
  • Product name : 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
  • Purity: 98%
  • Packaging: 5G
  • Price: ₹49048.08
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 14510
  • Product name : 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
  • Purity: ≥96.0% (HPLC)
  • Packaging: 100MG
  • Price: ₹3366.58
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 14510
  • Product name : 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
  • Purity: ≥96.0% (HPLC)
  • Packaging: 250MG
  • Price: ₹6375.93
  • Updated: 2022/06/14
  • Buy: Buy

BAPTA Chemical Properties,Usage,Production

  • Description BAPTA free acid (85233-19-8) is a selective extracellular Ca2+ chelator. It is a widely used calcium sponge for chelating Ca2+?outside of intact cells.1 It’s a useful tool to probe the involvement of extracellular Ca2+ in cellular signaling.2,3 Non-cell-permeable.
  • Chemical Properties White Solid
  • Uses Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels.
  • Uses As calcium chelator; 19F labelled forms for measurement of intracellular calcium.
  • Uses BAPTA is a highly selective calcium chelating reagent. Lipophilic diesters of the chelating agent 1,2-Bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) are used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE.
  • Definition ChEBI: A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene.
  • General Description In nature 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid (BAPTA) is a main metabolic product of BAPTA -AM (BAPTA-tetra(actoxymethyl ester), a neuro protective agent in cerebral ischemia, in rats.BAPTA is an intercellular Ca2+ chelator.
  • Biological Activity Selective calcium chelator.
  • storage Store at +4°C
  • References 1) Munoz et al. (2015), Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus; PLoS One, 10(9) e0138008 2) Wozniak et al. (2017), Extracellular Ca2+ is Required for Fertilization in the African Clawed Frog, Xenopus laevis; PLoS One, 12(1) e0170405 3) Didiasova et al. (2015), STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization; J. Biol. Chem., 290 11983
BAPTA Preparation Products And Raw materials
Raw materials
Preparation Products
Global(188)Suppliers
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BAPTA Spectrum
85233-19-8, BAPTARelated Search:
  • Fluorescent Labels & Indicators
  • Chelating Agents & Ligands
  • Aromatics
  • Amines
  • Aromatic
  • 信号转导通路激酶抑制剂
  • 抑制剂
  • 高端化学
  • 杂环类
  • 细胞信号和神经生物学
  • 芳烃
  • Biochemicals and Reagents
  • BioChemical
  • Calcium Signaling Research Tools
  • Calcium Chelators
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Intracellular Calcium Signaling
  • Fluorescent Probes, Labels, Particles and Stains
  • Detection
  • C22H20N2O10
  • C22H24N2O10
  • 化合物BAPTA,10 MM DMSO 溶液
  • BAPTA,EXTRACELLULAR CALCIUM CHELATOR
  • 化合物 BAPTA
  • 1,2-双(2-氨基苯氧基)乙烷-N,N,N'',N''-四乙酸
  • 1,2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸
  • 2,2,2,2-(((乙烷-1,2-叉基二(氧代))二(2,1-苯叉基))二(氮烷爪基))四乙酸
  • 钙选择性螯合剂
  • 1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸
  • 亚乙二氧基双(邻亚苯基次氮基)四乙酸
  • BAPTA四酸
  • 1,2-双(2-氨基苯氧基)乙烷-N,N,N`,N`-四乙酸 (BAPTA)
  • 2,2′-(亚乙二氧基)双苯胺-N,N,N′,N′-四乙酸
  • 1,2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸(>97.0%(HPLC))
  • 2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸
  • BAPTA,BAPTA四酸
  • N′-四乙酸 BAPTA 亚乙二氧基双(邻亚苯基次氮基)四乙酸
  • 2′-(亚乙二氧基)双苯胺-N
  • 85233-19-8
  • 1,2-Bis(2-Aminophenoxy)ethane-<i>N,N,N′,N′</i>-tetraacetic acid
  • BAPTA, 10 mM in DMSO
  • BAPTA, extracellular calcium chelator
  • Glycine,N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-
  • 2,2',2'',2'''-(((Ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanetriyl))tetraacetic acid
  • 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid
  • 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid
  • 1,2-Bis-(2-amino-phenoxy)ethane N,N,N',N'-tetraacetic
  • 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid &gt
  • CS-2002
  • BAPTA,97%
  • 1,2-Bis(2-aminophenoxy)-ethane-N,N,N'N'-tetraacetic acid,97%
  • BAPTA, Free Acid
  • 2,20-(ethylenedioxy)dianiline-n,n,n0, n0-tetraacetic Acid
  • 1,2-bis(o-aminophenoxy)ethane-n,n, n0,n0-tetraacetic Acid
  • 1,2-bis(2-aminophenoxy)ethane-n,n,n0, n0-tetraacetic Acid
  • 2,2'-((2-(2-(3-(Bis(carboxymethyl)amino)phenoxy)-ethoxy)phenyl)azanediyl)diacetic acid
  • BAPTA, >=98%