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BAPTA
BAPTA
- CAS No.85233-19-8
- Chemical Name:BAPTA
- CBNumber:CB3406887
- Molecular Formula:C22H24N2O10
- Formula Weight:476.43
- MOL File:85233-19-8.mol
BAPTA Property
- Melting point 177-179 °C
- Boiling point 575.89°C (rough estimate)
- Density 1.4482 (rough estimate)
- refractive index 1.6500 (estimate)
- RTECS MC0423000
- storage temp. 2-8°C
- solubility Soluble in dimethyl sulfoxide
- form Powder
- pka 1.40±0.10(Predicted)
- color White to off-white
- Water Solubility Soluble in water and sodium bicarbonate.
- λmax 209 nm, 254 nm, 203 nm, 274 nm
- Merck 14,957
- BRN 5192406
- Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- Biological Applications Calcium indicators; zinc indicators; treating acute cell death,cerebral infarction,myocardial infarction,hepatonecrosis,kidney ischemic necrosis,necrotizing pancreatitis,amyloidosis,atherosclerosis,diseases characteriz
- InChIKey FTEDXVNDVHYDQW-UHFFFAOYSA-N
- CAS DataBase Reference 85233-19-8(CAS DataBase Reference)
- FDA UNII K22DDW77C0
- UNSPSC Code 12352112
- NACRES NA.23
Safety
- Hazard Codes :Xi
- Risk Statements :36/37/38
- Safety Statements :26-36-37/39
- WGK Germany :3
- HS Code :29225090
-
NFPA 704:
1 2 0
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H315-H319-H335
- Precautionary statements P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
BAPTA Price
More Price(11)
- Brand: Sigma-Aldrich(India)
- Product number: A4926
- Product name : 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
- Purity: 98%
- Packaging: 250MG
- Price: ₹9655.9
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: A4926
- Product name : 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
- Purity: 98%
- Packaging: 1G
- Price: ₹12990
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: A4926
- Product name : 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
- Purity: 98%
- Packaging: 5G
- Price: ₹49048.08
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 14510
- Product name : 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
- Purity: ≥96.0% (HPLC)
- Packaging: 100MG
- Price: ₹3366.58
- Updated: 2022/06/14
- Buy: Buy
- Brand: Sigma-Aldrich(India)
- Product number: 14510
- Product name : 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid
- Purity: ≥96.0% (HPLC)
- Packaging: 250MG
- Price: ₹6375.93
- Updated: 2022/06/14
- Buy: Buy
BAPTA Chemical Properties,Usage,Production
- Description BAPTA free acid (85233-19-8) is a selective extracellular Ca2+ chelator. It is a widely used calcium sponge for chelating Ca2+?outside of intact cells.1 It’s a useful tool to probe the involvement of extracellular Ca2+ in cellular signaling.2,3 Non-cell-permeable.
- Chemical Properties White Solid
- Uses Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels.
- Uses As calcium chelator; 19F labelled forms for measurement of intracellular calcium.
- Uses BAPTA is a highly selective calcium chelating reagent. Lipophilic diesters of the chelating agent 1,2-Bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) are used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE.
- Definition ChEBI: A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene.
- General Description In nature 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid (BAPTA) is a main metabolic product of BAPTA -AM (BAPTA-tetra(actoxymethyl ester), a neuro protective agent in cerebral ischemia, in rats.BAPTA is an intercellular Ca2+ chelator.
- Biological Activity Selective calcium chelator.
- storage Store at +4°C
- References 1) Munoz et al. (2015), Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus; PLoS One, 10(9) e0138008 2) Wozniak et al. (2017), Extracellular Ca2+ is Required for Fertilization in the African Clawed Frog, Xenopus laevis; PLoS One, 12(1) e0170405 3) Didiasova et al. (2015), STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization; J. Biol. Chem., 290 11983
BAPTA Preparation Products And Raw materials
Raw materials
Preparation Products
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85233-19-8, BAPTARelated Search:
- RHOD-2, AM BAPTA BAPTA-AM Fura 2-AM Fluo 3-AM BAPTA TETRASODIUM SALT HYDRATE, 98+%,BAPTA-NA4,BAPTA, TETRASODIUM SALT BAPTA, 5,5'-DIBROMO-, TETRASODIUM SALT,5,5'-DIBROMO-BAPTA BAPTA POTASSIUM,BAPTA TETRAPOTASSIUM SALT,BAPTA(K+ SALT),BAPTA 4K BAPTA TETRAETHYL ESTER,BAPTA TETRAETHYL ESTER, 98+% FURA 2 PENTAPOTASSIUM SALT FURA 2 1-[2-(5-CARBOXYOXAZOL-2-YL)-6-AMINOBENZOFURAN-5-OXY]-2-(2'-AMINO-5'-METHYLPHENOXY)-ETHANE-N,N,N',N'-TETRAACETIC ACID, 5NA FLUO 3 INDO 1-AM NITR 5/AM INDO 1 PENTAPOTASSIUM SALT BAPTA, TETRACESIUM SALT BAPTA-TMFM
- Fluorescent Labels & Indicators
- Chelating Agents & Ligands
- Aromatics
- Amines
- Aromatic
- 信号转导通路激酶抑制剂
- 抑制剂
- 高端化学
- 杂环类
- 细胞信号和神经生物学
- 芳烃
- Biochemicals and Reagents
- BioChemical
- Calcium Signaling Research Tools
- Calcium Chelators
- Cell Biology
- Cell Signaling and Neuroscience
- Intracellular Calcium Signaling
- Fluorescent Probes, Labels, Particles and Stains
- Detection
- C22H20N2O10
- C22H24N2O10
- 化合物BAPTA,10 MM DMSO 溶液
- BAPTA,EXTRACELLULAR CALCIUM CHELATOR
- 化合物 BAPTA
- 1,2-双(2-氨基苯氧基)乙烷-N,N,N'',N''-四乙酸
- 1,2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸
- 2,2,2,2-(((乙烷-1,2-叉基二(氧代))二(2,1-苯叉基))二(氮烷爪基))四乙酸
- 钙选择性螯合剂
- 1,2-双(2-氨基苯氧基)-乙烷-N,N,N`,N`-四乙酸
- 亚乙二氧基双(邻亚苯基次氮基)四乙酸
- BAPTA四酸
- 1,2-双(2-氨基苯氧基)乙烷-N,N,N`,N`-四乙酸 (BAPTA)
- 2,2′-(亚乙二氧基)双苯胺-N,N,N′,N′-四乙酸
- 1,2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸(>97.0%(HPLC))
- 2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸
- BAPTA,BAPTA四酸
- N′-四乙酸 BAPTA 亚乙二氧基双(邻亚苯基次氮基)四乙酸
- 2′-(亚乙二氧基)双苯胺-N
- 85233-19-8
- 1,2-Bis(2-Aminophenoxy)ethane-<i>N,N,N′,N′</i>-tetraacetic acid
- BAPTA, 10 mM in DMSO
- BAPTA, extracellular calcium chelator
- Glycine,N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-
- 2,2',2'',2'''-(((Ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanetriyl))tetraacetic acid
- 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid
- 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid
- 1,2-Bis-(2-amino-phenoxy)ethane N,N,N',N'-tetraacetic
- 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid >
- CS-2002
- BAPTA,97%
- 1,2-Bis(2-aminophenoxy)-ethane-N,N,N'N'-tetraacetic acid,97%
- BAPTA, Free Acid
- 2,20-(ethylenedioxy)dianiline-n,n,n0, n0-tetraacetic Acid
- 1,2-bis(o-aminophenoxy)ethane-n,n, n0,n0-tetraacetic Acid
- 1,2-bis(2-aminophenoxy)ethane-n,n,n0, n0-tetraacetic Acid
- 2,2'-((2-(2-(3-(Bis(carboxymethyl)amino)phenoxy)-ethoxy)phenyl)azanediyl)diacetic acid
- BAPTA, >=98%