Preparation
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5-Nitroisatin

Preparation
5-Nitroisatin Structure
5-Nitroisatin
  • CAS No.611-09-6
  • Chemical Name:5-Nitroisatin
  • CBNumber:CB3396128
  • Molecular Formula:C8H4N2O4
  • Formula Weight:192.13
  • MOL File:611-09-6.mol
5-Nitroisatin Property
  • Melting point 251 °C (dec.) (lit.)
  • Boiling point 328.09°C (rough estimate)
  • Density 1.5513 (rough estimate)
  • refractive index 1.4900 (estimate)
  • storage temp. Sealed in dry,Room Temperature
  • pka 8.06±0.20(Predicted)
  • form Crystalline Powder
  • color Orange-yellow to orange
  • BRN 180223
  • InChIKey UNMYHYODJHKLOC-UHFFFAOYSA-N
  • CAS DataBase Reference 611-09-6(CAS DataBase Reference)
  • EWG's Food Scores 1
  • FDA UNII J4J633881Z
  • NIST Chemistry Reference 1H-indole-2,3-dione, 5-nitro-(611-09-6)
  • UNSPSC Code 12352100
  • NACRES NA.22
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302+H312+H332-H351
  • Precautionary statements P202-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313
5-Nitroisatin Price More Price(7)
  • Brand: Sigma-Aldrich(India)
  • Product number: N17807
  • Product name : 5-Nitroisatin
  • Purity: 97%
  • Packaging: 5G
  • Price: ₹5910.45
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: N17807
  • Product name : 5-Nitroisatin
  • Purity: 97%
  • Packaging: 25G
  • Price: ₹24150.58
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-B24962-22
  • Product name : 5-Nitroisatin, 98%
  • Purity: 
  • Packaging: 100g
  • Price: ₹31285
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ALFA India
  • Product number: ALF-B24962-14
  • Product name : 5-Nitroisatin, 98%
  • Purity: 
  • Packaging: 25g
  • Price: ₹10926
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: N0572
  • Product name : 5-Nitroisatin
  • Purity: 
  • Packaging: 5G
  • Price: ₹3200
  • Updated: 2022/05/26
  • Buy: Buy

5-Nitroisatin Chemical Properties,Usage,Production

  • Preparation Isatin 30 (14.7 g, 0.1 mol) was added to conc. H2SO4 (121 ml)  cooled to 0 ºC in an ice-salt bath. Fuming HNO3 (4.2 ml) was  added to this, drop by drop, in such a way that temperature should  not rise above 5 ºC. The reaction mixture was allowed to stand for  about 30 minutes and then poured over crushed ice (500 g). A yellow precipitate separated  immediately. The 5-Nitroisatin was filtered and washed with water and air dried to a constant  weight (15 g).  Yield : 85%
  • Chemical Properties orange-yellow to orange crystalline powder
  • Uses Reactant for preparation of:
    • Potential antibacterial and antifungal agents
    • spiro[indole-thiazolidinones] as a medicinally important scaffold
    • Potential antimycobacterial agents
    • Anticonvulsant agents
    • Inhibitors of human transglutaminase 2
    • Anthelmintic agents
    • Anti-human immunodeficiency virus (HIV) agents
    • Antimicrobial agents
    • Potential antitubercular agents
    • Inhibitors of acetylcholinesterase
  • Definition ChEBI: 5-Nitroisatin is a member of indoles. It has a role as an anticoronaviral agent.
5-Nitroisatin Preparation Products And Raw materials
Raw materials
Preparation Products
5-Nitroisatin Suppliers
Global(231)Suppliers
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5-Nitroisatin Spectrum
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