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N-NITROSOPIPERIDINE

CAS No.100-75-4
Chemical Name:N-NITROSOPIPERIDINE
CBNumber:CB3374481
Molecular Formula:C5H10N2O
Formula Weight:114.15
MOL File:100-75-4.mol

N-NITROSOPIPERIDINE Property

Melting point 170℃ (decomposition)
Boiling point 219℃
Density 1.06 g/mL(lit.)
refractive index 1.4933 (589.3 nm 19℃)
Flash point 11 °C
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form buffered aqueous solution
pka -3.18±0.20(Predicted)
color Light-yellow oil
biological source rabbit
Water Solubility 76.48g/L(24 ºC)
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 100-75-4(CAS DataBase Reference)
EWG's Food Scores 1-3
FDA UNII 6N066XUL4L
Proposition 65 List N-Nitrosopiperidine
IARC 2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System N-Nitrosopiperidine (100-75-4)
UNSPSC Code 41116105
NACRES NA.41

Safety

Hazard Codes :T,F
Risk Statements :25-40-39/23/24/25-23/24/25-11
Safety Statements :53-23-26-36/37/39-45-36/37-16-9
RIDADR :UN 2810 6.1/PG 3
WGK Germany :3
RTECS :TN2100000
HazardClass :6.1(b)
PackingGroup :III
Hazardous Substances Data :100-75-4(Hazardous Substances Data)
Toxicity :LD50 orl-rat: 200 mg/kg ZEKBAI 69,103,67

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H225-H301+H311+H331-H370
Precautionary statements P210-P260-P280-P301+P310-P311

N-NITROSOPIPERIDINE Price More Price(2)

Brand: Sigma-Aldrich(India)
Product number: SAB1300842
Product name : Anti-NP1(Nptx1) (C-term) antibody produced in rabbit
Purity: IgG fraction of antiserum, buffered aqueous solution
Packaging: 100μG
Price: ₹43789.5
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 40458
Product name : 1-Nitrosopiperidine solution
Purity: certified reference material, 5000?μg/mL in methanol
Packaging: 1ML
Price: ₹5705.7
Updated: 2022/06/14
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N-NITROSOPIPERIDINE Chemical Properties,Usage,Production

Chemical Properties light yellow oily liquid
Chemical Properties N-Nitrosopiperidine is a clear, yellow, oily liquid.
Uses A carcinogenic nitrosocompound.
Definition ChEBI: N-nitrosopiperidine is a nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite. It has a role as a carcinogenic agent, an apoptosis inducer, a mutagen and an environmental contaminant. It is a nitrosamine and a piperidine.
Synthesis Reference(s) Chemical and Pharmaceutical Bulletin, 36, p. 459, 1988 DOI: 10.1248/cpb.36.459
General Description Light yellow oil or liquid. May be a carcinogen.
Air & Water Reactions Water soluble.
Reactivity Profile N-NITROSOPIPERIDINE may react with strong oxidizing agents, especially peroxyacids. .
Health Hazard ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOPIPERIDINE emits highly toxic fumes.
Fire Hazard Flash point data are not available for N-NITROSOPIPERIDINE, but N-NITROSOPIPERIDINE is probably combustible.
Safety Profile Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Potential Exposure N-Nitrosopiperidine is found in some foods and tobacco smoke. Used as a research chemical.
Carcinogenicity N-Nitrosopiperidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required
Incompatibilities Nitrated organics range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction. Reaction with aliphatic amines can release carcinogenic nitrosamines. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Light and UV may cause decomposition
Waste Disposal Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.