ChemicalBook > CAS DataBase List > Nitrefazole

Nitrefazole

Nitrefazole Structure
Nitrefazole
  • CAS No.21721-92-6
  • Chemical Name:Nitrefazole
  • CBNumber:CB3356045
  • Molecular Formula:C10H8N4O4
  • Formula Weight:248.19
  • MOL File:21721-92-6.mol
Nitrefazole Property
  • Melting point 185-187°
  • storage temp. Refrigerator
  • solubility Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
  • form Solid
  • color Light Yellow to Yellow
  • FDA UNII VFD629099M
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Nitrefazole Chemical Properties,Usage,Production

  • Description Nitrefazole is an inhibitor of aldehyde dehydrogenase useful in the management of alcoholism. Cited advantages over disulfiram include longer duration of action, higher specificity (no inhibition of dopamine β-hydroxylase) and fewer side effects. It is generally recognized that the efficacy of such agents with respect to permanent abstinence is low. However, temporary abstinence and/or controlled drinking may facilitate supportive psychotherapy and/or delay the onset of severe alcoholic diseases.
  • Originator E. Merck (W. Germany)
  • Uses Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
  • Definition ChEBI: Nitrefazole is a member of imidazoles.
  • brand name ALTIMOL
  • World Health Organization (WHO) Nitrefazole, which is used in the treatment of alcoholism, was introduced in the early 1980s. By 1984 its use had been associated with hepatotoxic reactions, some of which were fatal. This led to its withdrawal in at least two countries. WHO has no information to suggest that preparations containing nitrefazole remain commercially available.
Nitrefazole Preparation Products And Raw materials
Raw materials
Preparation Products
Nitrefazole Suppliers
Global(14)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel： +8613564774135
  • Email：zijue.cai@tsbiochem.com
  • Country：United States
  • ProdList：19881
  • Advantage：58
  • Supplier： Energy Chemical
  • Tel：021-58432009<br/>400-005-6266
  • Email：marketing1@energy-chemical.com
  • Country：China
  • ProdList：44812
  • Advantage：58
  • Supplier： TargetMol Chemicals Inc.
  • Tel： 4008200310
  • Email：marketing@tsbiochem.com
  • Country：China
  • ProdList：24642
  • Advantage：58
Nitrefazole Spectrum
21721-92-6, NitrefazoleRelated Search:
  • 抑制剂
  • C10H8N4O4
  • 化合物 NITREFAZOLE
  • 硝法唑
  • 21721-92-6
  • 1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
  • 2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole
  • NITREFAZOLE
  • bt-985
  • 2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol
  • 2-methyl-4-nitro-1-(4-nitrophenyl)imidazole
  • 2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol
  • EMD 15700
  • 1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE
  • ALTIMOL

Home

My