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t-Boc-N-Amido-PEG3-propargyl

t-Boc-N-Amido-PEG3-propargyl Structure
t-Boc-N-Amido-PEG3-propargyl
  • CAS No.1333880-60-6
  • Chemical Name:t-Boc-N-Amido-PEG3-propargyl
  • CBNumber:CB33364014
  • Molecular Formula:C14H25NO5
  • Formula Weight:287.35
  • MOL File:1333880-60-6.mol
t-Boc-N-Amido-PEG3-propargyl Property
  • Boiling point 386.4±32.0 °C(Predicted)
  • Density 1.045±0.06 g/cm3(Predicted)
  • solubility Soluble in DMSO, DCM, DMF
  • pka 12.22±0.46(Predicted)
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319
  • Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

t-Boc-N-Amido-PEG3-propargyl Chemical Properties,Usage,Production

  • Description t-Boc-N-Amido-PEG3-propargyl enables formation of triazole linkage with azide-bearing compound via copper catalyzed Click Chemistry. Under mild acidic conditions, t-Boc group can be removed to yield the free amine.
  • Uses Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG3-propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-Amido-PEG3-propargyl Suppliers
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t-Boc-N-Amido-PEG3-propargyl Spectrum
1333880-60-6, t-Boc-N-Amido-PEG3-propargylRelated Search:
  • SiChem
  • 抑制剂
  • PEG系列产品-Propargy-PEG系列
  • 助剂
  • 1333800-60-6
  • 化合物 BOC-NH-PEG3-PROPARGYL
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  • 叔丁氧羰基-PEG3-丙炔
  • (2-(2-(2-(丙-2-炔-1-基氧基)乙氧基)乙氧基)乙基)氨基甲酸叔丁酯
  • 丙炔-三聚乙二醇-氨基叔丁酯
  • N-叔丁氧羰基-三聚乙二醇-丙炔基
  • 5,8,11-三氧杂-2-氮杂-13-炔十四烷酸叔丁酯
  • 1333880-60-6
  • tert-butyl N-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethyl]carbamate
  • Propargyl-PEG3-NHBoc/5,8,11-Trioxa-2-azatetradec-13-ynoic acid, 1,1-dimethylethyl ester
  • Propargyl-PEG4-Boc Amine
  • tert-Butyl (2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)carbamate
  • 5,8,11-Trioxa-2-azatetradec-13-ynoic acid, 1,?1-?dimethylethyl ester
  • Boc-NH-PEG3-propargyl
  • Boc-N-Amido-PEG3-Alkyne
  • Propargyl-PEG3-NHBoc
  • t-Boc-N-Amido-PEG3-propargyl

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