ChemicalBook > CAS DataBase List > Ald-PEG5-t-butyl ester
Ald-PEG5-t-butyl ester
Ald-PEG5-t-butyl ester
- CAS No.1446282-23-0
- Chemical Name:Ald-PEG5-t-butyl ester
- CBNumber:CB33062301
- Molecular Formula:C17H32O8
- Formula Weight:364.43
- MOL File:1446282-23-0.mol
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Ald-PEG5-t-butyl ester Chemical Properties,Usage,Production
- Description Ald-CH2-PEG5-t-butyl ester is an aldehyde PEG linker that is reactive with aminooxy-containing molecules. The t-butyl ester can be removed under acidic conditions for further conjugation.PEG5 spacer of the compound arimproves aqueous solubility.
- Uses Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
- IC 50 PEGs; Alkyl/ether
- References [1] Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034. DOI:10.1021/acschembio.9b00505
Ald-PEG5-t-butyl ester Preparation Products And Raw materials
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1446282-23-0, Ald-PEG5-t-butyl esterRelated Search:
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- Ald-CH2-PEG5-Boc
- CHO-PEG5-COOtBu
- CHOCH2-PEG5-COOtBu
- ALD-CH2-PEG5-T-BUTYL ESTER
- Ald-CH2-PEG5-CH2CH2COOtBu
- Ald-PEG5-t-butyl ester