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LANATOSIDE C

LANATOSIDE C Structure
LANATOSIDE C
  • CAS No.17575-22-3
  • Chemical Name:LANATOSIDE C
  • CBNumber:CB3298279
  • Molecular Formula:C49H76O20
  • Formula Weight:985.12
  • MOL File:17575-22-3.mol
LANATOSIDE C Property
  • Melting point 272-274°C
  • alpha D20 +33.4 to +33.7° (200 mg dry weight in 10 ml alcohol)
  • Boiling point 741.7°C (rough estimate)
  • Density 1.42±0.1 g/cm3 (20 ºC 760 Torr)
  • refractive index 1.7630 (estimate)
  • storage temp. -20°C
  • solubility DMSO:50.0(Max Conc. mg/mL);50.75(Max Conc. mM)
    Ethanol:2.0(Max Conc. mg/mL);2.03(Max Conc. mM)
  • pka 12.89±0.70(Predicted)
  • form Solid
  • color White to Off-White
  • Stability Hygroscopic
  • LogP 0.070
  • EWG's Food Scores 1
  • FDA UNII 5RR3JFZ771
  • ATC code C01AA06
  • UNSPSC Code 41116107
  • NACRES NA.25
Safety
  • Hazard Codes  :T
  • Risk Statements  :23/24/25
  • Safety Statements  :36/37/39-45
  • RIDADR  :UN 2811 6.1/PG 2
  • WGK Germany  :3
  • RTECS  :OE2100000
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H301-H330-H373
  • Precautionary statements P260-P264-P270-P271-P304+P340+P310-P314
LANATOSIDE C Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: L2261
  • Product name : Lanatoside C
  • Purity: ≥95%
  • Packaging: 100MG
  • Price: ₹12697.73
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: L2261
  • Product name : Lanatoside C
  • Purity: ≥95%
  • Packaging: 1G
  • Price: ₹45876.35
  • Updated: 2022/06/14
  • Buy: Buy

LANATOSIDE C Chemical Properties,Usage,Production

  • Chemical Properties White Solid
  • Originator Lanatozid C,Biofarm
  • Uses anti-acne
  • Uses Glycosides
  • Manufacturing Process 2000 parts of dry leaves of digitalis lanata are finely ground with 500 parts of sodium chloride, they are then wetted with 1000 parts of water and extracted with 30,000 parts of chloroform. The filtered extract is completely evaporated in vacuum at a low temperature and to the remaining residue are added 1000 parts of dry ether and the whole mixture is left under the ether until the thick viscous mass has been transformed into a hard body. The ether is then poured away and the residue is digested with 1000 parts of ether for about 2 hours under a reflux condenser. After cooling down the mixture, it is filtered, and the residue obtained, which is now in form of a brittle mass, which is then dried in vacuum in order to completely eliminate the remaining ether present, and pulverized. The pulverized mass is advantageously subjected once more to the treatment with ether. The yellow greenish powder thus obtained is then dissolved in 1000 parts of methyl alcohol and to the solution, so obtained a fine suspension of 30 parts lead hydroxide in 1000 parts water is added with stirring. The solution obtained is neutralized, stirred for about 2 hours, andfiltered, and the clear yellowish filtrate is preferably treated again with a small quantity of tannin precipitating substance. The clear filtrate thus obtained is concentrated in vacuum at a low temperature to about 200 parts, whereby the difficultly soluble portion of the glucoside mixture precipitates. The solution is then filtered. The precipitate is dissolved in a small quantity of methyl alcohol and is treated with a small quantity of water whereby the new product begins to precipitate in a crystalline form. By repeated crystallization from methyl alcohol, without addition of water, the glucoside may be obtained in the form of a perfectly pure compound; it does not change its properties even on further recrystallization. The glucoside, freshly crystallized from methyl alcohol and dried in vacuo, had MP: 248°C with decomposition, when heated rapidly. At 230°-235°C, the substance begins to sinter and becomes quite soft; the melting point, therefore, is not well defined.
  • Therapeutic Function Cardiotonic
  • Purification Methods Crystallise lanatoside C from MeOH. Its solubility is : 1/17000 (H2O), 1/45 (EtOH) and 1/1500-2000 (CHCl3). [Stoll et al. Helv Chim Acta 16 1049 1933, Stoll & Kreis Helv Chim Acta 35 1318 1952, Okada et al. Chem Pharm Bull Jpn 23 2039 1975, Beilstein 18 III/IV 2455.] It is cardiotonic.
LANATOSIDE C Preparation Products And Raw materials
Raw materials
Preparation Products
LANATOSIDE C Suppliers
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LANATOSIDE C Spectrum
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  • C49H76O20
  • 毛花甙丙,10 MM DMSO 溶液
  • (2R,3R,4S,6S)-6-(((2R,3S,4S,6R)-6-(((2R,3S,4S,6R)-6-(((3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-二羟基-10,13-二甲基-17-(5-氧-2,5-二氢呋喃-3-YL)十六氢-1H-环戊烷[A]菲-3-基)氧基)-4-羟基-2-甲基四氢-2H-吡喃-3-基)氧基)-4-羟基-2-甲基四氢-2H-吡喃-3-基)氧基)-2-甲基-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢
  • 地高辛EP杂质H(毛花苷C)
  • 地高辛杂质8(地高辛EP杂质H)
  • 地高辛EP杂质H(羊毛苷C)
  • 地高辛杂质H
  • 杂质H(毛花洋地黄苷C
  • 毛花洋地黄甙C
  • 地高辛EP杂质H( LANATOSIDE C)
  • 毛花苷C(甄准不供应)
  • DIGOXIN EP IMPURITY H (LANATOSIDE C)
  • 地高辛EP杂质H
  • 去乙酰基毛花洋地黄甙
  • 地高辛杂质H(EP)
  • 毛花甙C(地高辛杂质H)
  • 毛花洋地黄苷
  • 毛花苷C
  • 去乙酰毛花洋地黄甙
  • 毛花甙丙
  • 毛花洋地黄甙丙
  • 17575-22-3
  • Lanatoside C, 10 mM in DMSO
  • Lanatoside C -RM
  • 3β-[(β-D-glucopyranosyl-(1→4)-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide (lanatoside C),
  • (2R,3R,4S,6S)-6-(((2R,3S,4S,6S)-6-(((2R,3S,4S,6R)-6-(((3S,5R,8R,9S,10S,12R,13S,14S,17R)-12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-2-methyl-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl acetate
  • LANATOSIDE C USP/EP/BP
  • Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-3-O-acetyl-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
  • Digoxin EP Impurity H (Lanatoside C)

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