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SiraMesine, Lu-28-179

SiraMesine, Lu-28-179 Structure
SiraMesine, Lu-28-179
  • CAS No.224177-60-0
  • Chemical Name:SiraMesine, Lu-28-179
  • CBNumber:CB32685327
  • Molecular Formula:C30H32ClFN2O
  • Formula Weight:491.0392832
  • MOL File:224177-60-0.mol
SiraMesine, Lu-28-179 Property
  • Melting point 225 °C
  • storage temp. Sealed in dry,Room Temperature
  • solubility >49.1mg/mL in DMSO
  • form powder to crystal
  • color White to Light yellow
  • FDA UNII 39CG1EG1SS
Safety
  • HS Code  :2934.99.4700
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338
SiraMesine, Lu-28-179 Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: I1090
  • Product name : Siramesine Hydrochloride
  • Purity: 
  • Packaging: 5MG
  • Price: ₹3100
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: I1090
  • Product name : Siramesine Hydrochloride
  • Purity: 
  • Packaging: 25MG
  • Price: ₹10100
  • Updated: 2022/05/26
  • Buy: Buy

SiraMesine, Lu-28-179 Chemical Properties,Usage,Production

  • Uses Siramesine (Lu 28-179) hydrochloride is a potent sigma-2 receptor agonist. Siramesine hydrochloride has a subnanomolar affinity for sigma-2 receptors (IC50=0.12?nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17?nM). Siramesine hydrochloride triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity[1][2][3].
  • IC 50 Sigma 1 Receptor
  • storage Store at -20°C
SiraMesine, Lu-28-179 Preparation Products And Raw materials
Raw materials
Preparation Products
SiraMesine, Lu-28-179 Suppliers
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SiraMesine, Lu-28-179 Spectrum
224177-60-0, SiraMesine, Lu-28-179Related Search:
  • Inhibitors
  • 抑制剂
  • 生化试剂
  • 其他生化试剂
  • 小分子抑制剂，天然产物
  • 小分子抑制剂
  • C30H31FN2OHCl
  • 西拉美新盐酸盐,10 MM DMSO 溶液
  • 西拉美新盐酸盐, >98%
  • 化合物SIRAMESINE HYDROCHLORIDE
  • 1'-(4-(1-(4-氟苯基)-1H-吲哚-3-基)丁基)-3H-螺环[异苯并呋喃-1,4'-哌啶]盐酸盐
  • 西拉美新盐酸盐
  • 224177-60-0
  • Siramesine hydrochloride, 10 mM in DMSO
  • Xanthine Impurity 7
  • 1'-(4-(1-(4-Fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4'-piperidine] hydrochloride
  • Sigma Receptor,mitochondria,cathepsin,Ferroptosis,selectivity,lysosomes,Siramesine hydrochloride,Siramesine,Inhibitor,Lu 28-179,inhibit,cancer,death
  • 1'-[4-[1-(4-Fluorophenyl)-1H-indol-3-yl]butyl]-3H-spiro[isobenzofuran-1,4'-piperidine] Hydrochloride
  • Lu 28-179 hydrochlorid
  • LU 28-179 HYDROCHLORIDE
  • Siramesine, Lu-28-179 HCl
  • Siramesine.HCl
  • SiramesineLu-28-179 hydrochloride
  • SiraMesine, Lu-28-179 1'-[4-[1-(4-Fluorophenyl)-1H-indol-3-yl]butyl]spiro[isobenzofuran-1(3H),4'-piperidine] monohydrochloride
  • Siramesine hydrochloride 1'-[4-[1-(4-Fluorophenyl)-1H-indol-3-yl]butyl]spiro[isobenzofuran-1(3H),4'-piperidine] monohydrochloride
  • Siramesine (HCl salt), Lu-28-179
  • Siramesine hydrochloride, >=98%
  • 1'-[4-[1-(4-Fluorophenyl)-1H-indol-3-yl]butyl]spiro[isobenzofuran-1(3H),4'-piperidine] monohydrochloride
  • SiraMesine (hydrochloride)
  • SiraMesine, Lu-28-179

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