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Lecirelin

Lecirelin Structure
Lecirelin
  • CAS No.61012-19-9
  • Chemical Name:Lecirelin
  • CBNumber:CB3209815
  • Molecular Formula:C59H84N16O12
  • Formula Weight:1209.42
  • MOL File:61012-19-9.mol
Lecirelin Property
  • Density 1.44
  • storage temp. Store at -20°C
  • solubility DMSO : 12.1 mg/mL (10.00 mM)
  • form Solid
  • pka 9.82±0.15(Predicted)
  • color White to off-white
  • InChIKey XJWIEWPGHRSZJM-JUAATNMYNA-N
  • FDA UNII ZD8NZ8J5LN
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H360
  • Precautionary statements

Lecirelin Chemical Properties,Usage,Production

  • Uses Mammalian LHRHa containing Supergestran was used to stimulate the spermiation of tench males. Half dose of lecirelin was almost equally effective to induce the disappearance of the dominant follicle at Day 6 to 7 of the estrous cycle in three GnRH analogs of cattle.
  • Definition Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analog, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts. lecithin and buserelin, two nonapeptides, are used as the acetate. Lecirelin differs by substitution of D-tertiary leucine for glycine at position 6 and the replacement of glycine by ethylamide at position 10. Buserelin has a D-serine at position 6 and ethylamide at position 10.
  • in vitro Lecirelin (2.07 μM) significantly increases the tension and frequency of contractions in preovulatory follicles (PF), small follicular cysts (FC-S), and large follicular cysts (FC-L). Lecirelin increases the strips from preovulatory follicles contract significantly more than strips from cysts.
  • References [1] Picard-Hagen N, et al. Effect of gonadorelin, lecirelin, and buserelin on LH surge, ovulation, and progesterone in cattle. Theriogenology, 2015; 84: 177-183.
Lecirelin Preparation Products And Raw materials
Raw materials
Preparation Products
Lecirelin Suppliers
Global(137)Suppliers
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    career henan chemical co
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  • Country：China
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Lecirelin Spectrum
61012-19-9, LecirelinRelated Search:
  • 61012-19-9
  • 抑制剂
  • 小微企业
  • 药物多肽系列
  • 药物多肽
  • 标准品
  • 多肽-药物肽
  • 原料药
  • 医药原料药
  • 多肽
  • 多肽中间体
  • C59H84N16O12xC2H4O2
  • C59H84N16O12xC2HF3O2
  • C59H84N16O12
  • LECIRELIN游离态
  • 乐西瑞林醋酸盐
  • 兰瑞肽/LECIRELIN
  • 61012-19-9
  • (Des-Gly10,tBu-D-Gly6,Pro-NHEt 9)-LHRH trifluoroacetate
  • (Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH acetate salt
  • LEC
  • (Des-Gly??,tBu-D-Gly?,Pro-NHEt?)-LHRH trifluoroacetate salt
  • Lecirelin/Supergestran
  • Lecirelin acetate salt
  • LECIRELIN USP/EP/BP
  • (Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH trifluoroacetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt trifluoroacetate salt
  • (Des-Gly10, tBu-D-Gly6,Pro-NHEt 9)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-tBu-D-Gly-Leu-Arg-Pro-NHEt acetate salt
  • Lecirelin, BR
  • 1-9-LuteinizinghorMone-releasing factor (swine),6-(3-Methyl-D-valine)-9-(N-ethyl-L-prolinaMide)-
  • DalMarelin Acetate
  • Lecirelin Acetate
  • Lecirelin, (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, DalMarelin
  • LECIRELIN (DALMARELIN) ACETATE
  • Lecirelin (Dalmarelin) Acetate
  • Supergestran
  • 6-(3-Methyl-D-valine)-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing factor (pig)
  • (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, Lecirelin
  • (Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH (D-Tle6)-Leuprolide, (D-Tle6)-Leuprorelin, Lecirelin
  • LECIRELIN
  • GLP-HIS-TRP-SER-TYR-TLE-LEU-ARG-PRO-NHET
  • [D-TLE6,PRO-NHET9]-LHRH
  • (D-TLE6)-LEUPRORELIN
  • (D-TLE6)-LEUPROLIDE
  • (DES-GLY10,TBU-D-GLY6,PRO-NHET9)-LHRH
  • Lecirelin(6-(3-methyl-D-valine)-9-(N-ethyl-L-prolynamide)-10-deglycinamide)
  • PYR-HIS-TRP-SER-TYR-TBU-D-GLY-LEU-ARG-PRO-NHET
  • SUPERGESTRAN(TM)

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