ChemicalBook > CAS DataBase List > niga-ichigoside F1
niga-ichigoside F1
- CAS No.95262-48-9
- Chemical Name:niga-ichigoside F1
- CBNumber:CB31363365
- Molecular Formula:C36H58O11
- Formula Weight:666.843
- MOL File:95262-48-9.mol
niga-ichigoside F1 Property
- Melting point 232-234 °C
- Boiling point 775.0±60.0 °C(Predicted)
- Density 1.35±0.1 g/cm3(Predicted)
- pka 12.52±0.70(Predicted)
- form Solid
- color White to off-white
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
niga-ichigoside F1 Chemical Properties,Usage,Production
- Uses Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis[1].
- Definition ChEBI: 19alpha-hydroxyasiatic acid-28-O-beta-D-glucopyrannoside is a triterpenoid saponin that is 19alpha-hydroxyasiatic acid attached to a beta-D-glucopyranosyl residue at position 28 via a glycosidic linkage. It has been isolated from the leaves of Rosa laevigata. It has a role as a plant metabolite. It is a triterpenoid saponin, a pentacyclic triterpenoid, a monosaccharide derivative, a beta-D-glucoside and a tetrol. It is functionally related to a 19alpha-hydroxyasiatic acid. It derives from a hydride of an ursane.
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in vivo
Niga-ichigoside F1 (40 mg/kg; oral gavage; for 12 weeks) alleviates hepatic steatosis, possibly by significantly interacting with high-fat diet (HFD) to regulate lipid metabolism genes (including Srebp1c, Acc1, Fasn, Scd1, Cpt1a and Fabp5) in four-week-old male C57BL/6J mice[1].
- References [1] Shu-Fang Xia, et al. Niga-ichigoside F1 ameliorates high-fat diet-induced hepatic steatosis in male mice by Nrf2 activation. Food Funct. 2018 Feb 21;9(2):906-916. DOI:10.1039/c7fo01051f
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95262-48-9, niga-ichigoside F1Related Search:
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