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PROGLUMIDE, SODIUM SALT

PROGLUMIDE, SODIUM SALT Structure
PROGLUMIDE, SODIUM SALT
  • CAS No.99247-33-3
  • Chemical Name:PROGLUMIDE, SODIUM SALT
  • CBNumber:CB3125814
  • Molecular Formula:C18H27N2NaO4
  • Formula Weight:358.41
  • MOL File:99247-33-3.mol
PROGLUMIDE, SODIUM SALT Property
  • storage temp. Desiccate at RT
  • solubility H2O: soluble
  • form solid
  • color white
  • Water Solubility Soluble to 100 mM in water
  • EWG's Food Scores 1
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
PROGLUMIDE, SODIUM SALT Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: M006
  • Product name : Proglumide sodium salt
  • Purity: solid
  • Packaging: 100MG
  • Price: ₹17525.68
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: M006
  • Product name : Proglumide sodium salt
  • Purity: solid
  • Packaging: 500MG
  • Price: ₹108856.2
  • Updated: 2022/06/14
  • Buy: Buy

PROGLUMIDE, SODIUM SALT Chemical Properties,Usage,Production

  • Uses Proglumide sodium salt has been used to study the effects of proglumide on macronutrient selection in European sea bass Dicentrarchus labrax, L.
  • Biochem/physiol Actions Proglumide sodium salt is a non-peptide cholecystokinin receptor antagonist that has greater selectivity for the CCKA subtype. It selectively blocks central nervous system effects. Proglumide sodium salt is orally active.
  • in vivo

    Proglumide (250-750 mg/kg; intraperitoneal injection; adult male Sprague Dawley rats) treatment is significantly effective in ameliorating the seizure activities, cognitive dysfunctions, and cerebral oxidative stress[1].

    Animal Model:Adult male Sprague Dawley rats (200-250?g; 2 months old) are induced status epilepticus (SE)[1]
    Dosage:250 mg/kg, 500 mg/kg, and 750?mg/kg
    Administration:Intraperitoneal injection
    Result:Dose-dependently and significantly increased the latencies to seizure and SE. Significantly and dose-dependently attenuated Li-PC (SE) induced increase in thiobarbituric acid (TBARS) and catalase (CAT), attenuated Li-Pc induced decrease in SOD, and attenuated depletion of GSH and glutathione-S transferase (GST) in the hippocampus and striatum.
  • storage Desiccate at RT
PROGLUMIDE, SODIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
PROGLUMIDE, SODIUM SALT Suppliers
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PROGLUMIDE, SODIUM SALT Spectrum
99247-33-3, PROGLUMIDE, SODIUM SALTRelated Search:
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