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Tiazofurine

Tiazofurine Structure
Tiazofurine
  • CAS No.60084-10-8
  • Chemical Name:Tiazofurine
  • CBNumber:CB31179908
  • Molecular Formula:C9H12N2O5S
  • Formula Weight:260.269
  • MOL File:60084-10-8.mol
Tiazofurine Property
  • Melting point 145-146°
  • alpha D25 -9° (c = 0.5 in ethanol)
  • Density 1.4797 (rough estimate)
  • refractive index 1.6800 (estimate)
  • storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
  • solubility DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
  • form Solid
  • color White to Pale Beige
  • Stability Very Very Hygroscopic
  • NCI Dictionary of Cancer Terms tiazofurin
  • FDA UNII ULJ82834RE
  • NCI Drug Dictionary Riboxamide
  • ATC code L01XX18
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338

Tiazofurine Chemical Properties,Usage,Production

  • Chemical Properties White Solid
  • Uses Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5''-monophosphate (IMP) dehydrogenase.
  • Definition ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase).
  • brand name Tiazofurine is INN.
Tiazofurine Preparation Products And Raw materials
Raw materials
Preparation Products
Tiazofurine Suppliers
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Tiazofurine Spectrum
60084-10-8, TiazofurineRelated Search:
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  • 60084-10-8
  • Tiazofurin, 10 mM in DMSO
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  • Nucleoside Antimetabolite/Analog,NSC-286193,Inhibitor,Tiazofurin,inhibit,NSC286193,Orthopoxvirus
  • 2-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)thiazole-4-carboxamide
  • 2-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
  • 4-Thiazolecarboxamide, 2-β-D-ribofuranosyl-
  • 2-b-D-Ribofuranosyl-4-thiazolecarboxaMide
  • CI 909
  • 2-β-D-Ribofuranosylthiazole-4-carboxaMide
  • 2-β-D-Ribofuranosyl-4-thiazolecarboxaMide
  • Aids-014479
  • Aids014479
  • tiazofurin
  • Tiazofurine
  • 2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide
  • TCAR
  • Riboxamide
  • NSC-286-193
  • NSC-286193

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