Uses
Cloforex (Frenapyl) is an orally effective amphetamine-type anorexic and a precursor to Clophentermine. Cloforex can be used to induce foam cell accumulation in rats[1].
Definition
ChEBI: Cloforex is a member of amphetamines.
brand name
Avicol sl;Avicol-la;Chloferex;Frenapyl;Lipociden;Oberex;Vidipon;Zeisin.
World Health Organization (WHO)
Cloforex, a sympathomimetic phenethylamine derivative, was
introduced over twenty years ago for the treatment of obesity. Concern that its use
was associated with cases of pulmonary hypertension led to its withdrawal in
several countries. WHO has no information to suggest that this drug remains
commercially available.
References
[1] oodward SC. Induction and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine. J Toxicol Environ Health. 1981 Mar-Apr;7(3-4):569-83. DOI:
10.1080/15287398109530002
