ChemicalBook > CAS DataBase List > (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID

(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID

(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Structure
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
  • CAS No.81276-03-1
  • Chemical Name:(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
  • CBNumber:CB2767998
  • Molecular Formula:C20H32O3
  • Formula Weight:320.47
  • MOL File:81276-03-1.mol
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Property
  • Boiling point 464.5±33.0 °C(Predicted)
  • Density 0.983±0.06 g/cm3(Predicted)
  • Flash point 14 °C
  • storage temp. −20°C
  • pka 4.78±0.10(Predicted)
  • form Liquid (Density: 0.983±0.06 g/cm3)
  • color Colorless to light yellow
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319
  • Precautionary statements P210-P233-P280-P303+P361+P353-P337+P313-P370+P378

(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Chemical Properties,Usage,Production

  • Uses Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N''-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid >97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
  • Definition ChEBI: 14,15-Epoxy-5,8,11-eicosatrienoic acid is a long-chain fatty acid.
  • in vivo

    14,15-Epoxyeicosatrienoic acid (0.3 mg/kg i.v.) inhibits platelet aggregation in mouse cerebral arterioles[2].
    14,15-Epoxyeicosatrienoic acid (200 ng/ml) infusion into the hippocampus reversed Aβ deposition in the brains of 6-month-old male FAD mice[1].

  • IC 50 Human Endogenous Metabolite
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Suppliers
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(+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID Spectrum
81276-03-1, (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACIDRelated Search:
  • 抑制剂
  • 药靶配体
  • 生化试剂
  • (±)14(15)-EET
  • (±)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID
  • 化合物 14,15-EPOXYEICOSATRIENOIC ACID
  • 14,15-EET,花生四烯酸的细胞色素P450产物
  • 14,15-环氧基硅氧乙酸
  • 81276-03-1
  • (±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid, CAS 81276-03-1
  • "14,15-Epoxyeicosa-5,8,11-trienoic Acid D11 (14,15-EET)"
  • 5,8,11-Tridecatrienoic acid, 13-(3-pentyl-2-oxiranyl)-
  • 14,15-Epoxyeicosatrienoic acid
  • (5Z,8Z,11Z,14R,15S)-14,15-Epoxy-5,8,11-icosatrienoic acid
  • (5Z,8Z,11Z)-13-[(2R,3S)-3-Pentyloxiranyl]-5,8,11-tridecatrienoic acid
  • (5Z,8Z,11Z)-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienoic acid
  • 14,15-epoxy-5,8,11-eicosatrienoicacid
  • (+/-)14(15)-EPOXY-5Z,8Z,11Z-EICOSATRIENOIC ACID
  • 14(15)-EPETRE
  • (+/-)14(15)-EPETRE
  • 14,15-EET
  • (+/-)14,15-EET
  • (+/-)14,15-EPOXYEICOSA-5Z,8Z,11Z-TRIENOIC ACID

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