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11-DEOXY PROSTAGLANDIN F2ALPHA

11-DEOXY PROSTAGLANDIN F2ALPHA Structure
11-DEOXY PROSTAGLANDIN F2ALPHA
  • CAS No.37786-06-4
  • Chemical Name:11-DEOXY PROSTAGLANDIN F2ALPHA
  • CBNumber:CB2494474
  • Molecular Formula:C20H34O4
  • Formula Weight:338.48
  • MOL File:37786-06-4.mol
11-DEOXY PROSTAGLANDIN F2ALPHA Property
  • Boiling point 511.4±45.0 °C(Predicted)
  • Density 1.090±0.06 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
  • pka 4.76±0.10(Predicted)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H319-H360-H336
  • Precautionary statements P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

11-DEOXY PROSTAGLANDIN F2ALPHA Chemical Properties,Usage,Production

  • Description 11-deoxy PGF2α is a synthetic analog of PGF2α. It is a more potent agonist than PGF2α at inducing smooth muscle contractions of rabbit aorta, dog saphenous vein, and guinea pig trachea. It is approximately 20% less potent than U-46619.
  • Uses 11-Deoxyprostaglandin F2α is an activator for TREK-2 channels with EC50 of 0.294 μM. 11-Deoxyprostaglandin F2α inhibits the K2P channel TREK-1[1].
  • References [1] Dadi PK,et al., Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx. ACS Chem Neurosci. 2017 Mar 15;8(3):558-568. DOI:10.1021/acschemneuro.6b00301
11-DEOXY PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials
Raw materials
Preparation Products
11-DEOXY PROSTAGLANDIN F2ALPHA Suppliers
Global(23)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
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  • Supplier： TargetMol Chemicals Inc.
  • Tel： 4008200310
  • Email：marketing@tsbiochem.com
  • Country：China
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  • Supplier： Cayman Chemical Company
  • Tel：800-364-9897
  • Email：sales@caymanchem.com
  • Country：China
  • ProdList：27736
  • Advantage：58
11-DEOXY PROSTAGLANDIN F2ALPHA Spectrum
37786-06-4, 11-DEOXY PROSTAGLANDIN F2ALPHARelated Search:
  • 抑制剂
  • 高端化学
  • 制剂-激活剂
  • 化合物 11-DEOXY-PGF2A
  • 1-脱氧前列腺素F2Α
  • 化合物 T26376
  • 37786-06-4
  • Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-, (5Z,9α,13E,15S)-
  • 11deoxyPGF2a,11-deoxy-PGF-2a,11 deoxy PGF2a
  • 11-Deoxyprostaglandin F2α
  • 11-deoxy-PGF2a
  • 11-deoxyPGF2a
  • 11-deoxy PGF2a
  • 11-deoxy-Prostaglandin F2a
  • 1-deoxy Prostaglandin F2alpha
  • YRFLKMLJQWGIIZ-APRRXLQMSA-N
  • 1-deoxy Prostaglandin F<sub>2α</sub>
  • 11-deoxy Prostaglandin F2α
  • 11-DEOXY PROSTAGLANDIN F2ALPHA
  • 9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID

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