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(4E)-TCO-PEG4-amine

(4E)-TCO-PEG4-amine Structure
(4E)-TCO-PEG4-amine
  • CAS No.2243569-24-4
  • Chemical Name:(4E)-TCO-PEG4-amine
  • CBNumber:CB24849384
  • Molecular Formula:C19H36N2O6
  • Formula Weight:388.5
  • MOL File:2243569-24-4.mol
(4E)-TCO-PEG4-amine Property
  • Boiling point 517.1±50.0 °C(Predicted)
  • Density 1.09±0.1 g/cm3(Predicted)
  • solubility Soluble in DMSO, DCM, DMF
  • pka 11.95±0.46(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

(4E)-TCO-PEG4-amine Chemical Properties,Usage,Production

  • Description TCO-PEG4-amine is a heterobifunctional click chemistry reagent. Amine is very reactive with active NHS ester or with carboxylic acid in the presence of of activators suh as EDC. TCO moiety enable fast click chemistry with tetrazine molecule.
  • Uses TCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
  • IC 50 PEGs
  • References [1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001
(4E)-TCO-PEG4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
(4E)-TCO-PEG4-amine Suppliers
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    TargetMol Chemicals Inc.
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  • Supplier：
    Alfa Chemistry
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  • Email：Info@alfa-chemistry.com
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(4E)-TCO-PEG4-amine Spectrum
2243569-24-4, (4E)-TCO-PEG4-amineRelated Search:
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  • 2243569-24-4
  • TCO-PEG4-amine
  • (4E)-TCO-PEG4-amine

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