ChemicalBook > CAS DataBase List > SCOPOLAMINE METHYL NITRATE

SCOPOLAMINE METHYL NITRATE

SCOPOLAMINE METHYL NITRATE Structure
SCOPOLAMINE METHYL NITRATE
  • CAS No.6106-46-3
  • Chemical Name:SCOPOLAMINE METHYL NITRATE
  • CBNumber:CB2453455
  • Molecular Formula:C18H24N2O7
  • Formula Weight:380.4
  • MOL File:6106-46-3.mol
SCOPOLAMINE METHYL NITRATE Property
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H330-H300-H310
  • Precautionary statements P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
SCOPOLAMINE METHYL NITRATE Price More Price(2)
  • Brand: TCI Chemicals (India)
  • Product number: S0230
  • Product name : Scopolamine Methyl Nitrate
  • Purity: 
  • Packaging: 1G
  • Price: ₹6400
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: S0230
  • Product name : Scopolamine Methyl Nitrate
  • Purity: 
  • Packaging: 5G
  • Price: ₹24900
  • Updated: 2022/05/26
  • Buy: Buy

SCOPOLAMINE METHYL NITRATE Chemical Properties,Usage,Production

  • Originator Transderm ,Scop Novartis Consumer Health Inc.
  • Uses (-)Scopolamine Methylnitrate is a competitive antimuscarinic agent.
  • Manufacturing Process In a one-liter separatory funnel, 94 g (0.215 mol) of scopolamine hydrobromide trihydrate was dissolved in 250 ml of water, made alkaline by shaking with 40 g (1 mol) of sodium hydroxide in 150 ml of water, and the free base immediately extracted with ether. As scopolamine is somewhat soluble in water, the aqueous layer was saturated with potassium carbonate and again extracted with ether. The combined ether extracts were dried over anhydrous magnesium sulfate and the ether removed by distillation, leaving 65 g (0.214 mol; 100% yield) of nearly colorless oil. Then 100 g (1.05 mol) of cold methyl bromide was added to a chilled, 500-ml pressure flask containing the 65 g of scopolamine, the flask stoppered tightly with a clamp, and allowed to stand at room temperature for 96 hours. The flask was cooled before opening, excess methyl bromide removed by distilling, and the white solid washed thoroughly with dry ether. The yield of crude Nmethylscopolammonium bromide was 80 g (94 %t yield). The salt was recrystallized from 550 ml of alcohol; first crop, 70 g, MP: 212-214°C; second crop, 6 g, melting point 195-200°C. The combined crops were again recrystallized from 500 ml of alcohol; melting point 210-212°C. The third recrystallization from 600 ml of alcohol yielded 64 g, melting point 214- 216°C, a 75 % yield based on scopolamine hydro-bromide trihydrate starting material. N-Methylscopolammonium bromide may be dissolved in water. An equivalent of solution AgNO3 was added, a precipitated AgBr was filtered off. The filtrate was evaporated to dryness to give the desired Nmethylscopolammonium nitrate.
  • brand name Mesconit;Skopyle.
  • Therapeutic Function Anticholinergic, Spasmolytic
  • World Health Organization (WHO) Hyoscine methonitrate, a quaternary ammonium anticholinergic agent, was introduced in 1947 for use as a gastrointestinal antispasmodic. The action taken in Sweden relates to the use of this compound in preparations for suppressing the appetite. Preparations may remain available elsewhere.
SCOPOLAMINE METHYL NITRATE Preparation Products And Raw materials
Raw materials
Preparation Products
SCOPOLAMINE METHYL NITRATE Suppliers
Global(83)Suppliers
  • Supplier：
    Career Henan Chemica Co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：laboratory@coreychem.com
  • Country：China
  • ProdList：30231
  • Advantage：58
  • Supplier：
    AFINE CHEMICALS LIMITED
  • Tel：+86-0571-85134551
  • Email：sales@afinechem.com
  • Country：China
  • ProdList：15349
  • Advantage：58
  • Supplier：
    Alfa Chemistry
  • Tel：
  • Email：info@alfa-chemistry.com
  • Country：United States
  • ProdList：2344
  • Advantage：58
  • Supplier：
    Aston Chemical
  • Tel：13000000000
  • Email：sales@astonchem.com
  • Country：United States
  • ProdList：1634
  • Advantage：58
  • Supplier：
    LEAPCHEM CO., LTD.
  • Tel：+86-852-30606658
  • Email：market18@leapchem.com
  • Country：China
  • ProdList：43340
  • Advantage：58
  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
  • ProdList：52924
  • Advantage：58
  • Supplier：
    Suzhou ARTK Medchem Co., Ltd.
  • Tel：+86-512-68323658<br/>+86-18168183658
  • Email：sales1@artkmedchem.com
  • Country：China
  • ProdList：39003
  • Advantage：58
  • Supplier：
    Chongqing Chemdad Co., Ltd
  • Tel：+86-023-6139-8061<br/>+86-86-13650506873
  • Email：sales@chemdad.com
  • Country：China
  • ProdList：39927
  • Advantage：58
  • Supplier： Mainchem Co., Ltd.
  • Tel：+86-0592-6210733
  • Email：sale@mainchem.com
  • Country：China
  • ProdList：32343
  • Advantage：55
SCOPOLAMINE METHYL NITRATE Spectrum
6106-46-3, SCOPOLAMINE METHYL NITRATERelated Search:
  • Tropane Alkaloids
  • Biochemistry
  • Alkaloids
  • 中间体 有机碱
  • 有机碱
  • Alkaloids
  • Tropane Alkaloids
  • C18H24NO4NO3
  • C18H24N2O7
  • C17H21NO4CH3NO3
  • (1R,2R,4S,5S,7S)-7-(((S)-3-羟基-2-苯丙酰基)氧基)-9,9-二甲基-3-氧杂-9-氮杂环[3.3.1.02,4]壬烷-9-鎓硝酸盐
  • 硝酸甲酯东莨菪碱
  • 硝甲东莨菪碱
  • 甲基东莨菪碱硝酸盐
  • 东莨宕碱甲基硝酸
  • 东良宕碱甲基硝酸
  • 6106-46-3
  • (-)-Scopolamine methyl nitrate
  • Scopolamine (nitrate)
  • (-)Scopolamine Methylnitrate
  • Scopolamine Methyl Nitrate &gt
  • METHYL HYOSCINE NITRATE
  • Hyoscine methyl nitrate, Methscopolamine nitrate
  • (-)-N-methylhyoscinium nitrate
  • (-)-Scopolaminmethylnitrat
  • HYOSCINEMETHONITRATE
  • viscope
  • skopyl
  • skopolate
  • scopolamine,compdwithmethylnitrate(1:1)
  • n-methylscopolammoniumnitrate
  • methylscopolaminenitrate
  • methylnitrate,compdwithscopolamine
  • mescomine
  • itrate,(-)-tropate
  • epoxytropinetropatemethylnitrate
  • dwithmethylnitrate1:1)
  • alpha,-(hydroxymethyl)-benzeneaceticaci9-methyl-3-oxa-9-aztricyclo(3.3.1
  • 9-dimethyl--(7(s)-(1alpha,2beta,4beta,5alpha,7beta))--nitrate(salt)
  • 5-alpha-h-tropanium,6-beta,7-beta-epoxy-3-alpha-hydroxy-8-methyl-1-alpha-n
  • 4)non-7-ylester,(7(s)-(1alpha,2beta,4beta,5alpha,7beta))-.0comp
  • 1alphah,5alphah-tropanium,6beta,7beta-epoxy-3alpha-hydroxy-8-methyl-,nitrate,
  • ,9-dimethyl-,[7(s)-(1alpha,2beta,4beta,5alpha,7beta)]-,nitrate(salt)
  • HYOSCINE METHYL NITRATE
  • METHSCOPOLAMINE NITRATE
  • SCOPOLAMINE METHYL NITRATE
  • (-)SCOPOLAMINE METHYL NITRATE

Home

My