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Rifalazil

Rifalazil Structure
Rifalazil
  • CAS No.129791-92-0
  • Chemical Name:Rifalazil
  • CBNumber:CB2437664
  • Molecular Formula:C51H64N4O13
  • Formula Weight:941.07
  • MOL File:129791-92-0.mol
Rifalazil Property
  • Melting point 195-200° (dec)
  • Boiling point 1065.6±65.0 °C(Predicted)
  • Density 1.36±0.1 g/cm3(Predicted)
  • storage temp. 4°C, away from moisture
  • solubility DMSO: 8.33 mg/mL (8.85 mM)
  • pka 4.28±0.70(Predicted)
  • form Solid
  • color Blue to dark blue
  • FDA UNII S1976TE8QK
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Rifalazil Chemical Properties,Usage,Production

  • Uses Antibacterial (antimycobacterial).
  • Uses Rifalazil has been used as a part of multi drug regimen in the treatment of tuberculosis.
  • Definition ChEBI: Rifalazil is a phenoxazine.
  • in vivo

    Rifalazil (oral gavage; 20, 25, and 150 mg/kg; 6-8 weeks) combines with isoniazid (INH) for 6 weeks or greater significantly reduced the number of mice per group in which M. tuberculosis is detected in both spleens and lungs compared to the reductions for the early and late controls. And the addition of Pyrazinamide (PZA) does not significantly improve RLZ-INH therapy at any time point[2].

    Animal Model:Female CD-1 mice infected with 5.2 × 107?viable mycobacteria[2]
    Dosage:20, 25, and 150 mg/kg; 6-8 weeks
    Administration:Oral gavage
    Result:Combined with isoniazid (INH) showed its potential for short-course treatment of?Mycobacterium tuberculosis?infection.
Rifalazil Preparation Products And Raw materials
Raw materials
Preparation Products
Rifalazil Suppliers
Global(33)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Career Henan Chemica Co
  • Tel：+86-0371-86658258<br/>+8613203830695
  • Email：laboratory@coreychem.com
  • Country：China
  • ProdList：30231
  • Advantage：58
Rifalazil Spectrum
129791-92-0, RifalazilRelated Search:
  • 抑制剂
  • 标准品
  • C51H64N4O13
  • 化合物 T16749
  • 3'-羟基-5'-(4-异丁基-1-哌嗪)苯嗪利福霉素
  • 利福拉齐
  • 3'-羟基-5'-(4-异丁基-1-哌嗪)苯噁嗪利福霉素
  • 129791-92-0
  • Rifalazil USP/EP/BP
  • 5,12-Dihydroxy-2,4-dimethyl-10-[4-(2-methyl-propyl)-l-piperazinyl]-2,7-[oxy(5-acetoxy-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxo-l,ll,13-pentadecatriene-l,15-diyl)imino]-6H-benzofuro[4,5-a]phenoxazine-l(2H),6-dione
  • 1-Deoxy-1'-dehydro-1-oxo-3'-hydroxy-5'-[4-(2-methylpropyl)piperazino]rifamycin VIII
  • 3'-Hydroxy-5'-(4-isobutylpiperazinyl)benzoxazinorifamycin
  • KRM 1648
  • RIFALAZIL

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