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Malonamide

CAS No.108-13-4
Chemical Name:Malonamide
CBNumber:CB2418973
Molecular Formula:C3H6N2O2
Formula Weight:102.09
MOL File:108-13-4.mol

Malonamide Property

Melting point 172-175 °C (lit.)
Boiling point 191.38°C (rough estimate)
Density 1.3516 (rough estimate)
refractive index 1.5110 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in HCl.
pka 7.00±0.70(Predicted)
form powder to crystal
color White to Almost white
Water Solubility 180 g/L (20 ºC)
BRN 1751401
InChI InChI=1S/C3H6N2O2/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7)
InChIKey WRIRWRKPLXCTFD-UHFFFAOYSA-N
SMILES C(N)(=O)CC(N)=O
CAS DataBase Reference 108-13-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII QVQ8CNG255
NIST Chemistry Reference Propanediamide(108-13-4)
EPA Substance Registry System Propanediamide (108-13-4)
UNSPSC Code 12352100
NACRES NA.22

Safety

Safety Statements :22-24/25
WGK Germany :2
RTECS :ON9125000
TSCA :Yes
HS Code :29241900

NFPA 704:

	0
0		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H302-H315-H319-H332-H335
Precautionary statements P261-P280-P305+P351+P338

Malonamide Price More Price(10)

Brand: Sigma-Aldrich(India)
Product number: 129593
Product name : Malonamide
Purity: 97%
Packaging: 100G
Price: ₹3593.9
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: M0027
Product name : Malonamide
Purity:
Packaging: 25G
Price: ₹2200
Updated: 2022/05/26
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Brand: ALFA India
Product number: ALF-A17939-36
Product name : Malonamide, 98%
Purity:
Packaging: 500g
Price: ₹14356
Updated: 2022/05/26
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Brand: ALFA India
Product number: ALF-A17939-22
Product name : Malonamide, 98%
Purity:
Packaging: 100g
Price: ₹3477
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: M0027
Product name : Malonamide
Purity:
Packaging: 500G
Price: ₹11800
Updated: 2022/05/26
Buy: Buy

Malonamide Chemical Properties,Usage,Production

Description Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.
Chemical Properties White crystalline powder
Uses Malonamide is a reagent for fluorimetric determination of reducing carbohydrates. The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare earth elements from nitric acid medium.
Uses The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare-earth ions from nitric acid medium.
Uses Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.
Definition ChEBI: Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.
General Description The malonamide derivatives are obtained by the one-pot, five-component condensation reaction of isocyanide, Meldrum′s acid, arylidene malononitrile, and two amine molecules in CH₂Cl₂.
Hazard Mildly toxic by ingestion.
Synthesis The synthesis of Malonamide is as follows:
A typical reaction was carried out in a 10 mL flask. Benzonitrile (2 mmol), CuII-4 ? (0.2 g), acetaldoxime (6 mmol) and MeOH (4 mL) were stirred at 65 °C for 4 h. The solid was filtered, washed with MeOH and the filtrate evaporated. The residue was subjected to GC-MS analysis and NMR spectroscopy. The filtered catalyst can be recycled after drying at about 150 °C for 1 h.
Purification Methods Crystallise the amide from water. [Beilstein 2 IV 1887.]