Uses
Ceramide 1-phosphate is a bioactive lipid and one of the key components of sphingolipids. Ceramide 1-phosphate playing diverse roles in cellular behaviors such as cell differentiation, migration, proliferation and death[1].
Definition
ChEBI: N-octadecanoylsphingosine 1-phosphate is a ceramide 1-phosphate that is the N-octadecananoyl (stearoyl) derivative of sphingosine. It is functionally related to a sphingosine and an octadecanoic acid. It is a conjugate acid of a N-octadecanoylsphingosine 1-phosphate(2-).
Biochem/physiol Actions
Putative second messenger of agonist-stimulated sphingomyelin metabolism; may participate in cell regulation and transmembrane signaling.
References
[1] Li N, et al. Sphingolipid signaling in kidney diseases. Am J Physiol Renal Physiol. 2025 Feb 11. DOI:
10.1152/ajprenal.00193.2024
