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PHENAMIL

PHENAMIL Structure
PHENAMIL
  • CAS No.2038-35-9
  • Chemical Name:PHENAMIL
  • CBNumber:CB2384179
  • Molecular Formula:C12H12ClN7O
  • Formula Weight:305.72
  • MOL File:2038-35-9.mol
PHENAMIL Property
  • Melting point >181°C (dec.)
  • Density 1.65±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMSO: >15 mg/mL
  • form solid
  • pka 8.10±0.46(Predicted)
  • color yellow
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

PHENAMIL Chemical Properties,Usage,Production

  • Uses Phenamil Methanesulfonate Salt induced differentiation and peroxisome proliferator-activator receptor γ expression through ETS variant 4 in mouse preadipocyte
  • Definition ChEBI: Phenylamil is a member of pyrazines and a member of guanidines.
  • Enzyme inhibitor This amiloride derivative (FW = 306.73 g/mol; CAS 2038-35-9), also known as 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine carboxamide, irreversibly inhibits amiloride-sensitive Na+ channels. It is often supplied commercially as the methanesulfonate salt. Na+ channel blockers, such as phenamil and benzamil, are be alsoing explored as a way to counteract the hyperabsorption of NaCl in cystic fibrosis airways. Target(s): diamine oxidase; Na+ channels; and Na+ -driven flagellar motility.
PHENAMIL Preparation Products And Raw materials
Raw materials
Preparation Products
PHENAMIL Suppliers
Global(32)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel： +8613564774135
  • Email：zijue.cai@tsbiochem.com
  • Country：United States
  • ProdList：19889
  • Advantage：58
  • Supplier： J & K SCIENTIFIC LTD.
  • Tel： 18210857532
  • Email：jkinfo@jkchemical.com
  • Country：China
  • ProdList：96815
  • Advantage：76
  • Supplier：
  • Tel：821-50328103-801<br/>18930552037
  • Email：3bsc@sina.com
  • Country：China
  • ProdList：15839
  • Advantage：69
  • Supplier： TargetMol Chemicals Inc.
  • Tel： 4008200310
  • Email：marketing@tsbiochem.com
  • Country：China
  • ProdList：24683
  • Advantage：58
PHENAMIL Spectrum
2038-35-9, PHENAMILRelated Search:
  • 抑制剂
  • Voltage-gated Ion Channels
  • Sodium Channel Modulators
  • Ion Channels
  • Monovalent Ion Channels
  • Amiloride and Derivatives
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Irreversible inhibitor of amiloride-sensitive Na+ channels; derivative of amiloride.
  • C12H12ClN7O
  • C12H12ClN7OCH3SO3H
  • 化合物 PHENAMIL
  • 2038-35-9
  • 2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-
  • Phenamil methanesulfonate (free base)
  • 3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide
  • 3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide
  • 3,5-bis(azanyl)-N-[azanyl-(phenylamino)methylidene]-6-chloro-pyrazine-2-carboxamide
  • 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]pyrazine-2-carboxamide
  • phenylamil
  • phenamil methanesulfonate salt
  • 3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt
  • 3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE
  • PHENAMIL

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