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N-TETRADECYLPHOSPHONIC ACID

Physical state Shipping Condition

CAS No.4671-75-4
Chemical Name:N-TETRADECYLPHOSPHONIC ACID
CBNumber:CB2309695
Molecular Formula:C14H31O3P
Formula Weight:278.37
MOL File:4671-75-4.mol

N-TETRADECYLPHOSPHONIC ACID Property

Melting point 96-98°C
Boiling point 175.8°C
Density 0.998±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility ≥27.8 mg/mL in ETOH; insoluble in H2O; ≥2.27 mg/mL in DMSO with gentle warming and ultrasonic
pka 2.65±0.10(Predicted)
form Powder
color white to off-white
Water Solubility Soluble in ethanol, dimethyl sulfoxide and dimethyl formamide. Partially soluble in water.
InChIKey BVQJQTMSTANITJ-UHFFFAOYSA-N
CAS DataBase Reference 4671-75-4
EPA Substance Registry System Phosphonic acid, tetradecyl- (4671-75-4)
UNSPSC Code 12352300
NACRES NA.23

Safety

Risk Statements :36/37/38
Safety Statements :26-36/37/39
WGK Germany :2
RTECS :TA0460000
TSCA :Yes
HS Code :29319090

NFPA 704:

	0
0		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H303-H315-H319-H335
Precautionary statements P261-P280a-P304+P340-P305+P351+P338-P405-P501a

N-TETRADECYLPHOSPHONIC ACID Price More Price(10)

Brand: Sigma-Aldrich(India)
Product number: 736414
Product name : Tetradecylphosphonic acid
Purity: 98%
Packaging: 1G
Price: ₹7858.95
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 736414
Product name : Tetradecylphosphonic acid
Purity: 98%
Packaging: 5G
Price: ₹19755.63
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 736414
Product name : Tetradecylphosphonic acid
Purity: 98%
Packaging: 100G
Price: ₹101765.83
Updated: 2022/06/14
Buy: Buy

Brand: ALFA India
Product number: ALF-A17511-14
Product name : 1-Tetradecylphosphonic acid, 98%
Purity:
Packaging: 25g
Price: ₹108194
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: T3183
Product name : Tetradecylphosphonic Acid
Purity:
Packaging: 1G
Price: ₹5100
Updated: 2022/05/26
Buy: Buy

N-TETRADECYLPHOSPHONIC ACID Chemical Properties,Usage,Production

Physical state N-TETRADECYLPHOSPHONIC ACID is a white to off-white powder.
Shipping Condition Room Temperature; may vary elsewhere.
Uses 1-Tetradecylphosphonic acid is used to functionalize the surface of BaTiO3 nanoparticles.
Uses TDPA can be used to cap copper nanoparticles to protect them from oxidation. It may also be used in the synthesis of cadmium sulfate (CdS) core, which can be used in the fabrication of cadmium selenium (CdSe)/CdS core quantum dots (QDs). It may also be coated on caesium lead bromide (CsPbBr₃) perovskite quantum dots for the development of white light emitting diodes (wLED).
General Description Tetradecylphosphonic acid forms a self-assembled monolayer (SAM) to functionalize a variety of nanoparticles.
Biological Activity tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (lpa1), lpa2, and lpa3 receptors. the ic50 value for inhibition of lpa-induced calcium mobilization was 10 μm, 5.5 μm, and 3.1 μm, respectively. at a concentration of 10 μm, tetradecyl phosphonate activates a peroxisome proliferator-activated receptor γ reporter construct 4-fold when compared with the controls and partially inhibits autotaxin with an ic50 value of approximately 3 μm [1].lysophosphatidic acid (lpa), also known as autotaxin (atx), is a lipid signalling molecule formed by the hydrolysis of lysophosphatidyl choline by lysophospholipase d [2]. lpa signals through four different g protein-coupled receptors, named as lpa1/edg-2, lpa2/edg-4, lpa3/edg-7, and lpa4/gpr23 [3]. it has been reported that lpa was involved in activating peroxisome proliferator-activated receptor γ (pparγ) [4].
References [1]. durgam g g, virag t, walker m d, et al. synthesis, structure activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of pparγ, and inhibitors of autotaxin[j]. journal of medicinal chemistry, 2005, 48(15): 4919-4930.
[2]. tokumura a, majima e, kariya y, et al. identification of human plasma lysophospholipase d, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase[j]. journal of biological chemistry, 2002, 277(42): 39436-39442.
[3]. noguchi k, ishii s, shimizu t. identification of p2y9/gpr23 as a novel g protein-coupled receptor for lysophosphatidic acid, structurally distant from the edg family[j]. journal of biological chemistry, 2003, 278(28): 25600-25606.
[4]. mcintyre t m, pontsler a v, silva a r, et al. identification of an intracellular receptor for lysophosphatidic acid (lpa): lpa is a transcellular pparγ agonist[j]. proceedings of the national academy of sciences, 2003, 100(1): 131-136.