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AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Structure
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE
  • CAS No.55779-32-3
  • Chemical Name:AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE
  • CBNumber:CB2281528
  • Molecular Formula:C3H8N2O3
  • Formula Weight:120.11
  • MOL File:55779-32-3.mol
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Property
  • storage temp. -20°C
  • form Solid
  • color White to off-white
  • UNSPSC Code 12352209
  • NACRES NA.26
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: S4503
  • Product name : DL-Serine hydroxamate
  • Purity: seryl-tRNA synthetase inhibitor
  • Packaging: 250MG
  • Price: ₹35614.25
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: S4503
  • Product name : DL-Serine hydroxamate
  • Purity: seryl-tRNA synthetase inhibitor
  • Packaging: 1G
  • Price: ₹85669.05
  • Updated: 2022/06/14
  • Buy: Buy

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Chemical Properties,Usage,Production

  • Uses Serine has been used as an inhibitor of seryl-tRNA synthetase. DL-Serine hydroxamate is used to induce metabolic synthesis of guanosine 3′-diphosphate 5′-diphosphate (ppGpp) in E. coli by amino acid starvation. It is also used to synchronize cell cycle in E. coli cultures by inhibition of tRNA charging.
  • Definition ChEBI: Serine hydroxamate is a hydroxamic acid obtained by formal condensation of the carboxy group of serine with the amino group of hydroxylamine. It has a role as an EC 6.1.1.11 (serine--tRNA ligase) inhibitor. It is a hydroxamic acid and a serine derivative.
  • Biochem/physiol Actions Serine is involved in the one-carbon unit metabolism. It is associated with the biosynthesis of cysteine, ceramide, phosphatidylserine, purine and pyrimidine. In bacteria, it participates in tryptophan synthesis. Gluconeogenesis, one of the important biochemical processes, involves serine, particularly in ruminants. Protein phosphorylation is one such event that utilizes serine. Glycine, a metabolic product of serine, serves as an antioxidant and a neurotransmitter. D-serine is known to activate the N-methyl-D-aspartate (NMDA) receptors of the brain. Serine hydroxamate, a structural analogue of serine prevents seryl-tRNA (transfer ribonucleic acid) charging and thereby decreases phospholipid and nucleic acid synthesis in Escherichia coli.
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Suppliers
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AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE Spectrum
55779-32-3, AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATERelated Search:
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  • I - Z
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  • Isoleucine [Ile, I]
  • 生化试剂
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  • <sc>DL</sc>-Serine hydroxamate
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  • DL-SERINE HYDROXAMATE, SERYL-TRNA SY
  • SHX
  • (Z)-2-aMino-N,3-dihydroxypropaniMidic acid
  • DL-Serine hydroxaMate seryl-tRNA synthetase inhibitor
  • rac-(R*)-2-Amino-3-hydroxypropanehydroxamic acid
  • AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE

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