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2-Methoxyphenylboronic acid

CAS No.5720-06-9
Chemical Name:2-Methoxyphenylboronic acid
CBNumber:CB2264149
Molecular Formula:C7H9BO3
Formula Weight:151.96
MOL File:5720-06-9.mol

2-Methoxyphenylboronic acid Property

Melting point 105-110 °C (lit.)
Boiling point 319.3±44.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka 8.55±0.58(Predicted)
form Crystals or Crystalline Powder
color Off-white
Water Solubility Insoluble in water.
BRN 3030981
InChI InChI=1S/C7H9BO3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5,9-10H,1H3
InChIKey ROEQGIFOWRQYHD-UHFFFAOYSA-N
SMILES B(C1=CC=CC=C1OC)(O)O
CAS DataBase Reference 5720-06-9(CAS DataBase Reference)
UNSPSC Code 12352103
NACRES NA.06

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :37/39-26-36
WGK Germany :3
TSCA :No
HazardClass :IRRITANT
HS Code :29163990

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H335-H315-H319
Precautionary statements P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

2-Methoxyphenylboronic acid Price More Price(10)

Brand: Sigma-Aldrich(India)
Product number: 445231
Product name : 2-Methoxyphenylboronic acid
Purity: 95%
Packaging: 1G
Price: ₹1753.65
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 445231
Product name : 2-Methoxyphenylboronic acid
Purity: 95%
Packaging: 5G
Price: ₹7609.98
Updated: 2022/06/14
Buy: Buy

Brand: TCI Chemicals (India)
Product number: M1261
Product name : 2-Methoxyphenylboronic Acid (contains varying amounts of Anhydride)
Purity:
Packaging: 1G
Price: ₹2500
Updated: 2022/05/26
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Brand: ALFA India
Product number: ALF-B21071-14
Product name : 2-Methoxybenzeneboronic acid, 97%
Purity:
Packaging: 25g
Price: ₹25966
Updated: 2022/05/26
Buy: Buy

Brand: TCI Chemicals (India)
Product number: M1261
Product name : 2-Methoxyphenylboronic Acid (contains varying amounts of Anhydride)
Purity:
Packaging: 5G
Price: ₹6900
Updated: 2022/05/26
Buy: Buy

2-Methoxyphenylboronic acid Chemical Properties,Usage,Production

Description 2-Methoxyphenylboronic acid is an arylboronic acid. Arylboronic acids can be widely used as safe and environmentally friendly new aromatization reagents for scientific research and production of various fine chemicals containing aryl structures, such as pharmaceuticals, pesticides, and advanced materials. The reactions of arylboronic acids with halogenates play a pivotal role in today's drug synthesis, and such reactions were pioneered by Japanese scientists Suzuki's team, which won the Nobel Prize in Chemistry in 2010.
Chemical Properties white to light yellow crystal powder
Uses 2-Methoxylphenylboronic acid is a phenylboronic acid used to investigate boron function in plants. It is used in Suzuki reaction, organic reaction that is classified as a coupling reaction where the coupling partners are a boronic acid with a halide catalyzed by a palladium(0) complex.
Preparation Under the protection of nitrogen, add magnesium (2.9 g, 1.2 times) and tetrahydrofuran (20 ml) and dibromoethane (1.9 g) to a 250 ml three-necked flask with a dropping funnel; then add 2-methoxybromobenzene (17.1 g, 0.1 mol), trimethyl borate (36.8 g, 3.5 times) and tetrahydrofuran (50 ml) as solvent to the dropping funnel. Heat to 40 ℃, activate the magnesium powder, and then slowly add the mixture in the dropping funnel dropwise, control the speed to the reaction temperature does not exceed 60 ℃, add the reaction after stirring until the magnesium basically disappeared, and then heat the reflux reaction for 6 hours. Stop heating, cool to room temperature, hydrolyze with 5% dilute hydrochloric acid to pH<2. Distillation to recover THF solvent, as the solvent is reduced, the product precipitated; cooling and filtration, recrystallization in methanol/water can be obtained 2-methoxyphenylboronic acid.