Chemical Properties
clear pale yellow to yellow liquid. Soluble in ethanol, diethyl ether, and benzene; insoluble in water.
Uses
3-Methoxybenzaldehyde is used to prepare 3-(3-methoxy-phenyl)-1-phenyl-propenone by reaction with benzldehyde. It is used as an eluent for mono-13C isotopomers of vanillin in normal phase silica gel chromatography. It acts as an inhibitor of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism.
Definition
ChEBI: 3-methoxybenzaldehyde is a member of the class of benzaldehydes in which the hydrogen at position 3 of benzaldehyde has been replaced by a methoxy group. It has a role as a Brassica napus metabolite. It is a member of benzaldehydes and a monomethoxybenzene.
Preparation
3-Methoxybenzaldehyde is obtained by the reaction of m-hydroxybenzaldehyde and dimethyl sulfate.
General Description
m-Anisaldehyde has significant antifungal activity against
Candida sp., including the azole-resistant strains.
Safety Profile
Mutation data reported. Whenheated to decomposition it emits acrid smoke andirritating vapors.
Purification Methods
Wash it with saturated aqueous NaHCO3, then H2O, dry it with anhydrous MgSO4 and distil it under reduced pressure under N2. Store it under N2 in sealed glass ampoules. [Beilstein 8 IV 241.]
