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RICININE

CAS No.524-40-3
Chemical Name:RICININE
CBNumber:CB2202950
Molecular Formula:C8H8N2O2
Formula Weight:164.16
MOL File:524-40-3.mol

RICININE Property

Melting point 201.5°
Boiling point 291.62°C (rough estimate)
Density 1.2739 (rough estimate)
refractive index 1.6000 (estimate)
Flash point 2℃
storage temp. -20°C
solubility DMSO: slightly soluble,Methanol: slightly soluble
form A solid
pka -4.93±0.62(Predicted)
Water Solubility 2.7g/L(10 ºC)
CAS DataBase Reference 524-40-3
FDA UNII 130UFS7AE0

Safety

Hazard Codes :T,Xn,F
Risk Statements :25-36-20/21/22-11
Safety Statements :45-36/37-16
RIDADR :UN 2811 6.1 / PGIII
WGK Germany :3
RTECS :QT3100000

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H301
Precautionary statements P301+P310

RICININE Price More Price(1)

Brand: Sigma-Aldrich(India)
Product number: SMB00079
Product name : Ricinine
Purity: ≥95% (LC/MS-ELSD)
Packaging: 1MG
Price: ₹25925.88
Updated: 2022/06/14
Buy: Buy

RICININE Chemical Properties,Usage,Production

Description First isolated by Tuson from the seeds of Ricinus communis (castor-oil seed), the alkaloid was subsequently examined by Soave, Schultze and Evans. The base crystallizes from H20 in colourless prisms or leaflets and sublimes at 170-lS0°C/ 20 mm. It is soluble in hot H20 or CHCI3, only sparingly so in EtOH and insoluble in petroleum ether, is neutral in reaction, optically inactive and forms no normal salts although the mercurichloride, m.p. 204°C has been prepared. The alkaloid reduces KMn04 and may be hydrolyzed by alkalies to MeOH and ricininic acid which forms brilliant, slender needles, m.p. 296-8°C (dec.). The structure of ricinine has been confirmed by synthesis from 4-chloroquinoline. Other syntheses have also been achieved. The base is not particularly toxic and the poisonous character of castor-oil seeds has been shown to be due to a more complex substance, ricin, the toxicity of which may be destroyed by heating.
Chemical Properties White Solid
Uses Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. Ricinine also has bactericidal effects on three pests and heptaprotective activity.
Uses An alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). It is a central nervous system stimulant that could potentially be a cognition-enhancing agent used for the treatment of human amnesias. It also has bactericidal effects on t
Definition ChEBI: Ricinine is a pyridine alkaloid, a pyridone and a nitrile.
Hazard Toxic by ingestion.
Safety Profile A poison by ingestion and subcutaneous route. When heated to decomposition it emits toxic vapors of NOx.
References Tuson.,J. Chern. Soc., 17,195 (1864)
Soave., Chern. Soc. Abstr., i, 386 (1896)
Schultze., ibid, i, 42 (1898)
Evans., J. Arner. Chern. Soc., 22, 39 (1900)
Maqueen, Philippe., Cornpt. rend., 138, 506 (1904)
Maqueen, Philippe., ibid, 139, 840 (1904)
Winterstein, Keller, Weinhagen., Arch. Pharrn., 255,513 (1917)
Bottcher., Ber., 51,673 (1918)
Spath, Tschelnitz., Monatsh., 42,251 (1921)
Spath, Koller., Ber., 56, 880, 2454 (1923)
Spath, Koller., ibid, 58,2124 (1925)
Schroeter et ai., ibid, 65, 432 (1932)
Reitmann., Chern. Abstr., 29,4359 (1935)