ChemicalBook > CAS DataBase List > H-MET-SER-OH
H-MET-SER-OH
H-MET-SER-OH
- CAS No.14517-43-2
- Chemical Name:H-MET-SER-OH
- CBNumber:CB2200330
- Molecular Formula:C8H16N2O4S
- Formula Weight:236.29
- MOL File:14517-43-2.mol
H-MET-SER-OH Property
- Boiling point 548.6±50.0 °C(Predicted)
- Density 1.334±0.06 g/cm3(Predicted)
- storage temp. −20°C
- pka 2.93±0.10(Predicted)
- CAS DataBase Reference 14517-43-2
Safety
- WGK Germany :3
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
H-MET-SER-OH Chemical Properties,Usage,Production
- Uses Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].
- Definition ChEBI: Met-Ser is a dipeptide composed of L-methionine and L-serine joined by a peptide linkage. It has a role as a metabolite. It is functionally related to a L-methionine and a L-serine.
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References
[1] Diana H?jmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. DOI:10.1016/j.ejpb.2010.12.009
[2] Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954.
H-MET-SER-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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14517-43-2, H-MET-SER-OHRelated Search:
- H-MET-THR-OH ASN-ALA-SER-TRP-SER-ASN-LYS-SER-LEU-GLU-GLN-ILE-TRP-ASN-ASN-MET-THR H-ALA-GLY-ALA-VAL-VAL-GLY-GLY-LEU-GLY-GLY-TYR-MET-LEU-GLY-SER-ALA-MET-SER-OH H-TYR-SER-ALA-TYR-PRO-ASP-SER-VAL-PRO-MET-MET-SER-OH H-LEU-ARG-ALA-GLU-GLN-THR-ASP-ALA-ALA-VAL-LYS-ASN-TRP-MET-THR-OH NEF MN (68-82) NEF (66-80) BOC-MET-SER-OH GP120-W61D-50 GP41 (620-632) H-ARG-GLU-ARG-MET-SER-OH AGTTSTLQEQIGWMT H-MET-SER-OH
- Peptides
- Dipeptides and Tripeptides
- Dipeptides
- 多肽
- 化学生物学
- 多肽合成
- Biochemicals and Reagents
- Amino Acids and Peptides
- BioChemical
- Dipeptides
- Dipeptides and Tripeptides
- H-MET-SER-OHH-MET-SER-OH
- L-蛋氨酰-L-丝氨酸
- 14517-43-2
- Methionylserine
- (S)-2-((S)-2-Amino-4-(methylthio)butanamido)-3-hydroxypropanoic acid
- L-Serine, L-methionyl-
- H-MET-SER-OH
- L-METHIONYL-L-SERINE
- L-MET-SER
- MET-SER
- N-L-Methionyl-L-serine
- Met-Ser-OH
- L-Met-L-Ser-OH
- 76: PN: WO2012021247 SEQID: 87 claimed protein