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LATRUNCULIN B

LATRUNCULIN B Structure
LATRUNCULIN B
  • CAS No.76343-94-7
  • Chemical Name:LATRUNCULIN B
  • CBNumber:CB2186645
  • Molecular Formula:C20H29NO5S
  • Formula Weight:395.51
  • MOL File:76343-94-7.mol
LATRUNCULIN B Property
  • alpha D24 +112° (c = 0.48 in chloroform)
  • storage temp. -20°C
  • solubility DMSO: soluble
  • form solid
  • color light yellow
  • optical activity +120.123 （CHCl3）
  • Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
  • FDA UNII LW7U308U7U
  • UNSPSC Code 12352200
  • NACRES NA.77
Safety
  • WGK Germany  :3
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
LATRUNCULIN B Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: 428020
  • Product name : Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem
  • Purity: Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fo
  • Packaging: 1MG
  • Price: ₹21209.99
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: L5288
  • Product name : Latrunculin B from Latruncula magnifica
  • Purity: ≥80% (HPLC), solid
  • Packaging: 1MG
  • Price: ₹31760.55
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: 428020
  • Product name : Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem
  • Purity: Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fold more potent than cytochalasins.
  • Packaging: 5MG
  • Price: ₹59070
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 428020
  • Product name : Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem
  • Purity: Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fo
  • Packaging: 5MG
  • Price: ₹59070
  • Updated: 2022/06/14
  • Buy: Buy

LATRUNCULIN B Chemical Properties,Usage,Production

  • Description Latrunculin B (76343-94-7) inhibits actin polymerization and disrupts microfilament organization.1 Significantly more potent than cytochalasins in the disruption of microfilament mediated processes2, causes shortening and thickening of stress fibers. Active in cell culture.3,4?Effective doses for latrunculin B vary depending upon cell type but are frequently in the low micromolar range. Note: Latrunculin B is slowly inactivated by fetal bovine serum.
  • Uses Latrunculin B is an actin polymerization inhibitor.
  • Uses Latrunculin B from Latruncula magnifica has been used for actin depolymerisation in various experiments. It has also been used as a component in bone marrow-derived dendritic cell (BMDC) complete medium, to study the formation of tubules from phagosomes in dendritic cells.
  • Uses In elucidation of molecular mechanisms of motile processes.
  • Definition ChEBI: A macrolide consisting of a 14-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica.
  • General Description Latrunculin B is a macrocyclic toxin, which is produced by Latruncula magnifica.
  • Biochem/physiol Actions Primary TargetActin polymerization
  • storage Store at -20°C
  • References 1) Coue?et al. (1987),?Inhibition of actin polymerization by latrunculin; FEBS Lett.,?213?316 2) Spector?et al. (1989),?Latrunculins-novel marine macrolides that disrupt microfilament organization and affect cell growth; Cell Motil. Cytoskeleton,?13?127 3) Wakatsuki?et al. (2001),?Effects of cytochalasin D and latrunculin B on mechanical properties of cells; J. Cell. Sci.,?114?1025 4) Cha?et al. (2004),?The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1/2 but is dependent on an intact actin cytoskeleton as determined by FRAP; Prog. Clin. Biol. Res.,?230 4 5) Herrera (2021), Cell cultures, transfection and treatments. protocols.io???https://dx.doi.org/10.17504/protocols.io.77ehrje [Focus Citation]
LATRUNCULIN B Preparation Products And Raw materials
Raw materials
Preparation Products
LATRUNCULIN B Suppliers
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LATRUNCULIN B Spectrum
76343-94-7, LATRUNCULIN BRelated Search:
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  • Latrunculin B, <i>Latrunculia magnifica</i>
  • Latrunculin B from <i>Latruncula magnifica</i>
  • Latrunculin B, actin polymerization inhibitor
  • Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem
  • (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone
  • 2-Thiazolidinone, 4-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-, (4R)-
  • (4R)-4-[(1R,4S,5Z,9Z,13R,15R)-15-hydroxy-4,9-dimethyl-11-oxo-12,16-dioxabicyclo[11.3.1]heptadeca-5,9-dien-15-yl]-1,3-thiazolidin-2-one
  • LATRUNCULIN B
  • Latrunculin B from Latruncula magnifica
  • NSC 339663
  • LATRUNCULIN B, LUTRUNCULIA MAGNIFICA
  • LatrunculinBfromLutrunculiamagnifica
  • LAT-B
  • LATRUNCULIN B, LATRUNCULIA MAGNIFICA

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