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BROMODICHLOROMETHANE

CAS No.75-27-4
Chemical Name:BROMODICHLOROMETHANE
CBNumber:CB2186236
Molecular Formula:CHBrCl2
Formula Weight:163.83
MOL File:75-27-4.mol

BROMODICHLOROMETHANE Property

Melting point −55 °C(lit.)
Boiling point 87 °C(lit.)
Density 1.98 g/mL at 25 °C(lit.)
vapor pressure 50 at 20 °C (Dreisbach, 1952)
refractive index n20/D 1.497(lit.)
Flash point 87-89°C
storage temp. 2-8°C
solubility water: insoluble
form liquid
color Clear, colorless liquid
Water Solubility 3.032g/L(30 ºC)
Merck 14,1417
BRN 1697005
Henry's Law Constant In seawater (salinity 30.4‰): 5.52, 10.51, and 18.97 at 0, 10, and 20 °C, respectively (Moore et al., 1995)
Stability Light Sensitive, Volatile
CAS DataBase Reference 75-27-4(CAS DataBase Reference)
FDA UNII 7LN464CH2O
Proposition 65 List Bromodichloromethane
IARC 2B (Vol. 52, 71) 1999
EPA Substance Registry System Dichlorobromomethane (75-27-4)
UNSPSC Code 77101502
NACRES NA.24

Safety

Hazard Codes :Xn,T,F
Risk Statements :22-37/38-40-41-39/23/24/25-23/24/25-11
Safety Statements :26-36/39-45-36/37-16-36/37/39-36-7
RIDADR :2810
WGK Germany :3
RTECS :PA5310000
F :8
HazardClass :6.1
PackingGroup :III
HS Code :29037990
Hazardous Substances Data :75-27-4(Hazardous Substances Data)
Toxicity :LD50 in male, female mice (mg/kg): 450, 900 orally (Bowman)

NFPA 704:

	0
2		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordDanger
Hazard statements H302-H315-H318-H335-H351
Precautionary statements P201-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310-P308+P313

BROMODICHLOROMETHANE Price More Price(3)

Brand: Sigma-Aldrich(India)
Product number: 48615
Product name : Bromodichloromethane solution
Purity: certified reference material, 200?μg/mL in methanol
Packaging: 1ML
Price: ₹2872.8
Updated: 2022/06/14
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Brand: Sigma-Aldrich(India)
Product number: 40046
Product name : Bromodichloromethane solution
Purity: certified reference material, 5000?μg/mL in methanol
Packaging: 1ML
Price: ₹5639.2
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: B1011
Product name : Bromodichloromethane (stabilized with Ethanol)
Purity: min. 96.0 %
Packaging: 25G
Price: ₹16300
Updated: 2022/05/26
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BROMODICHLOROMETHANE Chemical Properties,Usage,Production

Description Bromodichloromethane is a liquid. Molecularweight=163.8; Specific gravity (H2O:1)=1.98; Boilingpoint=90℃. Odor threshold=about 1675 mg/m3. Solublein water.
Chemical Properties clear colorless to yellowish liquid
Chemical Properties Bromodichloromethane (BDCM) is a colorless, heavy, non-burnable/non-flammable liquid. It was formerly used as a flame retardant, a solvent for fats and waxes and because of its high density for mineral separation. Now, it is only used as a reagent or intermediate in organic chemistry. Small amounts of BDCM are also made in chemical plants for use in laboratories or in making other chemicals. On contact with hot surfaces or flames, BDMC decomposes forming toxic and corrosive gases, including hydrogen bromide and hydrogen chloride and reacts with strong bases, strong oxidants, and magnesium. BDMC is found in chlorinated drinking water as a consequence of the reaction between chlorine, added during water treatme
Uses As a chemical intermediate for organic synthesis and as a laboratory reagent; formerly used as a solvent and flame retardant. Currently, the major source of bromodichloromethane in the environment is from its formation as a by-product during chlorination of water.
Uses A volatile halogenated methane present in trace amounts in drinking water as a result of the water treatment process. It is also present in swimming pools due to chlorination and can be used as tracers to identify water leaks. It is useful as chain transfer agents in PVC polymerization.
Uses Chemical reagent, intermediate in organic synthesis.
Definition ChEBI: A one-carbon compound that is methane substituted by a bromo and two chloro groups. It occurs as a contaminant in drinking water.
Synthesis Reference(s) Tetrahedron Letters, 28, p. 2769, 1987 DOI: 10.1016/S0040-4039(00)96205-1
General Description Clear colorless liquid.
Air & Water Reactions Slightly water soluble.
Reactivity Profile BROMODICHLOROMETHANE may react with strong bases and magnesium. Incompatible with oxidizing materials .
Health Hazard SYMPTOMS: Symptoms of exposure to BROMODICHLOROMETHANE may include irritation of the skin, eyes, mucous membranes and respiratory tract. It may also cause narcosis. Other symptoms may include nausea, dizziness and headache. It may also cause liver and kidney damage. Central nervous system effects may also occur.
Health Hazard On ingestion, BDMC causes damage to the kidneys, liver, and impaired functio
Fire Hazard Literature sources indicate that BROMODICHLOROMETHANE is nonflammable.
Biochem/physiol Actions Bromodichloromethane (BDCM) induces steatohepatitic injury in human liver. BDCM induces the cell proliferation in different tissues and kidney damage by renal tuble cell proliferation in male F344 rats.
Safety Profile Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Brand Cl-. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and BROMIDES.
Potential Exposure This compound may find applicationin organic synthesis.
First aid If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contactsthe skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove fromexposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing hasstopped and CPR if heart action has stopped. Transferpromptly to a medical facility. When this chemical hasbeen swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit.
Carcinogenicity Bromodichloromethane is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Source MCLG: zero; MCL: 0.08 mg/L. Total for all trihalomethanes cannot exceed a concentration of 0.08 mg/L. In addition, a DWEL of 700 μg/L was recommended (U.S. EPA, 2000).
By-product in chlorination of drinking water and use of fire extinguishers (quoted, Verschueren, 1983).
Environmental Fate Biological. Bromodichloromethane showed significant degradation with gradual adaptation in a static-culture flask-screening test (settled domestic wastewater inoculum) conducted at 25 °C. At concentrations of 5 and 10 mg/L, percent losses after 4 wk of incubation were 59 and 51, respectively. At a substrate concentration of 5 mg/L, 8% was lost due to volatilization after 10 d (Tabak et al., 1981).
Chemical/Physical. The estimated hydrolysis half-life in water at 25 °C and pH 7 is 137 yr (Mabey and Mill, 1978). Reported products of hydrolysis include carbon monoxide, hydrochloric and hydrobromic acids (Ellington et al., 1993; Kollig, 1993).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities at pH 5.3 were 7.9, 1.9, 0.47, and 0.12 mg/g, respectively (Dobbs and Cohen, 1980).
storage Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in a refrigerated space in a tightly closedcontainer. Protect from light. A regulated, marked areashould be established where this chemical is handled,used, or stored in compliance with OSHA Standard1910.1045.
Shipping Toxic, liquids, organic, n.o.s. requires a shippinglabel of “POISONOUS/TOXIC MATERIALS.” It falls intoHazard Class 6.1 and Packing Group III.
Toxics Screening Level The initial risk screening level (IRSL) for bromodichloromethane is calculated according to Rule 231 (1 ): IRSL = 0.06 μg/m3