Chemical Properties
Crystalline solid; melts at 170 °C (338 °F);aqueous solubility data not available; dissolves in organic solvents.
Production Methods
The commercial synthesis of procyazine involves the cyclisation of cyanuric chloride with cyclopropylamine, followed by substitution with a branched alkyl nitrile such as 2-amino-2-methylpropanenitrile. This yields the active compound.
Health Hazard
Oral toxicity in rates was found to be moderate; possibly toxic by other routes of exposures; contains a nitrile functional group andis structurally related to cyanazine; moderately toxic by skin absorption; teratogeniceffect in experimental animals.
LD50 oral (rat): 290 mg/kg.
Mechanism of action
Selective, systemic action with residual and foliar activity. Inhibits photosynthesis (photosystem II).
