ChemicalBook > CAS DataBase List > Benmoxine
Benmoxine
Benmoxine
- CAS No.7654-03-7
- Chemical Name:Benmoxine
- CBNumber:CB21178090
- Molecular Formula:C15H16N2O
- Formula Weight:240.3
- MOL File:7654-03-7.mol
Benmoxine Property
- Melting point 93-94°
- Boiling point 383.02°C (rough estimate)
- Density 1.0611 (rough estimate)
- refractive index 1.6390 (estimate)
- pka 12.29±0.23(Predicted)
- FDA UNII XC9FY2SGBG
Safety
- RIDADR :3249
- HazardClass :6.1(b)
- PackingGroup :III
- Toxicity :LD50 oral in rat: 675mg/kg
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Benmoxine Chemical Properties,Usage,Production
- Originator Neuralex,Millot
- Definition ChEBI: Benmoxin is a member of benzoic acids.
- Manufacturing Process A mixture of 29.6 parts of acetylhydrazine, 48 parts of acetophenone and 140 parts of ethanol is heated under reflux for 18 hours and is then cooled to 20-25°C and filtered. The solid residue, M.P. 135-136°C, is washed with diethyl ether and dried at 40°C. 28.5 parts of this dried product in 180 parts of methanol is shaken in an atmosphere of hydrogen under a pressure of 100 atmospheres and at a temperature of 25°C in the presence of 3 parts of a 5% palladium on carbon catalyst until the theoretical amount of hydrogen is absorbed. The mixture is filtered and the filtrate is evaporated. The residue is fractionally distilled under reduced pressure and there is thus obtained 1-(α- methylbenzyl)-2-acetylhydrazine, B.P. 182-186°C/15 mm, M.P. 72-74°C.
- Therapeutic Function Antidepressant
Benmoxine Preparation Products And Raw materials
Raw materials
Preparation Products
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7654-03-7, BenmoxineRelated Search:
- 7654-03-7
- BENZOIC ACID N'-(1-PHENYL-ETHYL)-HYDRAZIDE
- BENZOIC ACID N'-(1-PHENYL-ETHYL)-HYDRAZIDE
- N'-(1-phenylethyl)benzohydrazide
- Benzoic acid, 2-(1-phenylethyl)hydrazide
- Neuralex
- Nerusil
- Benzoic acid 2-(α-methylbenzyl) hydrazide
- 75-20-C
- 1-Benzoyl-2-(α-methylbenzyl)hydrazine
- Benmoxine