ChemicalBook > CAS DataBase List > (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Structure
(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid
  • CAS No.80544-17-8
  • Chemical Name:(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid
  • CBNumber:CB2110046
  • Molecular Formula:C8H9N3O5S
  • Formula Weight:259.24
  • MOL File:80544-17-8.mol
(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Property
  • Melting point >160°C (dec.)
  • Boiling point 481.1±51.0 °C(Predicted)
  • Density 1?+-.0.1 g/cm3(Predicted)
  • storage temp. Refrigerator, under inert atmosphere
  • solubility DMSO (Slightly), Methanol (Slightly, Heated)
  • pka 2.40±0.10(Predicted)
  • form Solid
  • color White to Off-White
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Chemical Properties,Usage,Production

  • Uses (Z)-2-(2-amino-4-thiazolyl)-2-methoxycarbonylmethoxyiminoacetic acid (cefixime side chain acid) is an important side chain for the synthesis of the third and fourth generation cephalosporins It is of great economic and practical value to strengthen its research and development.
  • Uses (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid can be used as an intermediate in organic synthesis.
  • Preparation

    The synthesis of cefixime side chain acid takes tert-butyl acetoacetate as raw material, through the steps of oximation, etherification, chlorination, cyclization and hydrolysis, to synthesize (Z)-2-(2-amino Thiazol-4-yl)-2-methoxycarbonylmethoxyiminoacetic acid.

(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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(Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid Spectrum
80544-17-8, (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acidRelated Search:
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  • Cefixime Impurity 39
  • Mannitol Impurity 65
  • Cefixime side chain acid( TBKWCLS)
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  • (Z)-2-(tert-Methoxycarbonyl Methoxyimino)-2-(2-Aminothiazol-...
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  • (2-AMINOTHIAZOL-4-YL)-METHOXYCARBONYLMETHOXYIMINOACETIC ACID
  • Cefixime Impurity 9
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  • (Z)-2-(Methoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)acetic acid
  • (Z)-2-(2-AMINOTHIAZOL-4-YL)-2-METHOXYCARBONYLMETHOXYIMINOACETIC ACID
  • MICAAcid
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